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Items 1 to 100 of about 790
1. Glaab F, Rieder J, Klein R, Choquesillo-Lazarte D, Melero-Garcia E, García-Ruiz JM, Kunz W, Kellermeier M: Precipitation and Crystallization Kinetics in Silica Gardens. Chemphyschem; 2017 Feb 17;18(4):338-345

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the present study, this dynamic behavior was investigated for silica gardens based on iron and cobalt chloride by means of two synchrotron-based techniques, which allow the determination of concentration profiles and time-resolved monitoring of diffraction patterns, thus giving direct insight into the progress of dissolution and crystallization phenomena in the system.
  • On the basis of the collected data, a kinetic model is proposed to describe the relevant reactions on a fundamental physicochemical level.

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  • [Copyright] © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
  • [Cites] Angew Chem Int Ed Engl. 2012 Apr 27;51(18):4317-21 [22431259.001]
  • [Cites] Chem Rev. 2015 Aug 26;115(16):8652-703 [26176351.001]
  • [Cites] Langmuir. 2012 Feb 28;28(8):3714-21 [22035594.001]
  • [Cites] Phys Chem Chem Phys. 2007 Jan 7;9(1):110-6 [17164892.001]
  • [Cites] Angew Chem Int Ed Engl. 2015 Jul 6;54(28):8184-7 [25968422.001]
  • [Cites] Langmuir. 2011 Apr 5;27(7):3286-93 [21391635.001]
  • [Cites] Biochemistry. 2016 May 17;55(19):2806-11 [27115539.001]
  • [Cites] Chemphyschem. 2017 Feb 17;18(4):338-345 [28001337.001]
  • [Cites] Angew Chem Int Ed Engl. 2008;47(51):9900-3 [19003836.001]
  • [Cites] J Am Chem Soc. 2010 Dec 22;132(50):17859-66 [21117693.001]
  • [Cites] Nanoscale. 2013 Aug 7;5(15):7054-65 [23807473.001]
  • [Cites] Nanoscale. 2011 Jan;3(1):265-71 [21069231.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11537-41 [15284444.001]
  • [Cites] J Am Chem Soc. 2003 Apr 9;125(14):4338-41 [12670257.001]
  • [Cites] Phys Chem Chem Phys. 2016 Sep 28;18(36):24850-8 [27397509.001]
  • [Cites] Methods Enzymol. 2013;532:45-69 [24188762.001]
  • (PMID = 28001337.001).
  • [ISSN] 1439-7641
  • [Journal-full-title] Chemphyschem : a European journal of chemical physics and physical chemistry
  • [ISO-abbreviation] Chemphyschem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; X-ray absorption spectroscopy / X-ray diffraction / kinetics / self-assembly / silica gardens
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2. Auclair C, Pierre A, Voisin E, Pepin O, Cros S, Colas C, Saucier JM, Verschuere B, Gros P, Paoletti C: Physicochemical and pharmacological properties of the antitumor ellipticine derivative 2-(diethylamino-2-ethyl)9-hydroxy ellipticinium-chloride, HCl. Cancer Res; 1987 Dec 1;47(23):6254-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical and pharmacological properties of the antitumor ellipticine derivative 2-(diethylamino-2-ethyl)9-hydroxy ellipticinium-chloride, HCl.
  • 2-(Diethylamino-2-ethyl)9-hydroxyellipticinium-chloride, HCl (DHE), a new congener of the antitumor agent elliptinium acetate (Celiptium) (NMHE), has recently been selected for phase I clinical trials.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Animals. Cell Line. Chemistry, Physical. Colonic Neoplasms / drug therapy. DNA / metabolism. Leukemia L1210 / drug therapy. Leukemia P388 / drug therapy. Melanoma / drug therapy. Mutagenicity Tests. Physicochemical Phenomena. Salmonella / drug effects

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  • (PMID = 3677074.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Alkaloids; 0 / Antineoplastic Agents; 0 / Ellipticines; 117VLW7484 / ellipticine; 81531-57-9 / detalliptinium; 9007-49-2 / DNA
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3. Kodym A, Zawisza T, Taberska J, Kukuła H: Physicochemical and microbiological properties of eye drops containing cefuroxime. Acta Pol Pharm; 2006 Jul-Aug;63(4):293-9

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  • [Title] Physicochemical and microbiological properties of eye drops containing cefuroxime.
  • The purpose of the studies was to examine the influence of the additives and storage temperature on physicochemical properties and on the antimicrobial activity of cefuroxime in the eye drops.
  • The eye drops were 1% sterile aqueous solutions of cefuroxime in citrate buffer of pH 6.15-6.20, preserved with 0.002% thiomersal or 0.001% phenylmercuric borate with 0.4% beta-phenylethyl alcohol.
  • As the criteria of the qualitative assessment of freshly prepared eye drops and during their storage, the following properties were considered: organoleptic analysis (color, clarity, and smell), sterility, pH, osmotic pressure, density, and viscosity, antimicrobial activity of cefuroxime and preservation efficiency of thiomersal and phenylmercuric borate in the eye drops.
  • The antimicrobial activity of cefuroxime in the drops stored for 30 days at the temperature of 4 degrees C did not decrease.
  • Thiomersal at the concentration over 0.003%, 0.005% benzalkonium chloride and 0.01% chlorhexidine diacetate were not compatible with cefuroxime in the drops.
  • [MeSH-major] Anti-Infective Agents / chemistry. Anti-Infective Agents / pharmacology. Cefuroxime / chemistry. Cefuroxime / pharmacology
  • [MeSH-minor] Bacteria / drug effects. Chemistry, Physical. Fungi / drug effects. Microbial Sensitivity Tests. Ophthalmic Solutions. Osmotic Pressure. Physicochemical Phenomena. Sterilization. Viscosity

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  • (PMID = 17203867.001).
  • [ISSN] 0001-6837
  • [Journal-full-title] Acta poloniae pharmaceutica
  • [ISO-abbreviation] Acta Pol Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Ophthalmic Solutions; O1R9FJ93ED / Cefuroxime
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4. Lagerberg JW, Williams M, Moor AC, Brand A, van der Zee J, Dubbelman TM, VanSteveninck J: The influence of merocyanine 540 and protoporphyrin on physicochemical properties of the erythrocyte membrane. Biochim Biophys Acta; 1996 Jan 31;1278(2):247-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The influence of merocyanine 540 and protoporphyrin on physicochemical properties of the erythrocyte membrane.
  • The interaction of the red cell membrane with merocyanine 540 or protoporphyrin led to four phenomena, most probably interrelated. (i) The morphology changed from the normal discoid to an echinocytic form.
  • The pathway of this temporary leak seems to be unrelated to the Na+/K+ -ATPase, the K+/Cl- and the Na+/K+/Cl- cotransport systems, the Ca2+-activated Gardos pathway, the oxidation/deformation-activated leak pathway and the so-called residual transport route.
  • Despite the morphological changes, K+-leakage induced by mechanical stress was not increased. (iv) During osmotic swelling, the critical hemolytic volume was found to be increased in the presence of either merocyanine 540 or protoporphyrin.
  • The increase critical volume protected erythrocytes against osmotic hemolysis.
  • [MeSH-minor] Cell Membrane Permeability. Chemistry, Physical. Erythrocyte Deformability / drug effects. Erythrocytes / cytology. Erythrocytes / drug effects. Erythrocytes / physiology. Hemolysis. Humans. Osmosis. Phospholipids / blood. Physicochemical Phenomena. Viscosity

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  • (PMID = 8593283.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / Phospholipids; 0 / Photosensitizing Agents; 0 / Protoporphyrins; 0 / Pyrimidinones; 58823-12-4 / merocyanine dye
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5. López-Corcuera B, Alcántara R, Vázquez J, Aragón C: Hydrodynamic properties and immunological identification of the sodium- and chloride-coupled glycine transporter. J Biol Chem; 1993 Jan 25;268(3):2239-43
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  • [Title] Hydrodynamic properties and immunological identification of the sodium- and chloride-coupled glycine transporter.
  • We have recently reported the purification of the native sodium- and chloride-coupled glycine transporter from pig brain stem (López-Corcuera, B.
  • Taken together, the results reported herein corroborate the identity of the 100-kDa band as the sodium- and chloride-coupled glycine transporter and also suggest that in its native state the transporter is a monomeric protein.
  • [MeSH-major] Amino Acid Transport Systems, Neutral. Brain Stem / chemistry. Carrier Proteins / chemistry. Chlorides / metabolism. Sodium / metabolism
  • [MeSH-minor] Animals. Antigens / immunology. Centrifugation, Density Gradient. Chemistry, Physical. Cholic Acid. Cholic Acids / metabolism. Chromatography, Gel. Deuterium. Glycine Plasma Membrane Transport Proteins. Immune Sera / immunology. Immunosorbent Techniques. Molecular Weight. Physicochemical Phenomena. Swine

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  • (PMID = 8420992.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Amino Acid Transport Systems, Neutral; 0 / Antigens; 0 / Carrier Proteins; 0 / Chlorides; 0 / Cholic Acids; 0 / Glycine Plasma Membrane Transport Proteins; 0 / Immune Sera; 75621-03-3 / 3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate; 9NEZ333N27 / Sodium; AR09D82C7G / Deuterium; G1JO7801AE / Cholic Acid
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6. Qi H, Li L, Huang C, Li W, Wu C: Optimization and physicochemical characterization of thermosensitive poloxamer gel containing puerarin for ophthalmic use. Chem Pharm Bull (Tokyo); 2006 Nov;54(11):1500-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimization and physicochemical characterization of thermosensitive poloxamer gel containing puerarin for ophthalmic use.
  • The influence of the other ingredients on the physicochemical properties of the formulation was also investigated.
  • Hydroxypropyl-beta-cyclodextrin (HPCD) enhanced the gelation temperature and reduced the gel strength and the bioadhesive force, while puerarin and benzalkonium chloride (BC) had a comparatively smaller influence.
  • But only sodium chloride appears to be a promising isotonicity agent for the poloxamer gel containing puerarin, HPCD and BC.
  • [MeSH-major] Isoflavones / chemistry. Poloxamer / chemistry. Temperature
  • [MeSH-minor] Benzalkonium Compounds / chemistry. Chemistry, Physical. Gels. Ophthalmic Solutions. Physicochemical Phenomena. beta-Cyclodextrins / chemistry

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  • (PMID = 17077546.001).
  • [ISSN] 0009-2363
  • [Journal-full-title] Chemical & pharmaceutical bulletin
  • [ISO-abbreviation] Chem. Pharm. Bull.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Benzalkonium Compounds; 0 / Gels; 0 / Isoflavones; 0 / Ophthalmic Solutions; 0 / beta-Cyclodextrins; 106392-12-5 / Poloxamer; 94035-02-6 / 2-hydroxypropyl-beta-cyclodextrin; Z9W8997416 / puerarin
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7. Paloglou A, Martakidis K, Gavril D: An inverse gas chromatographic methodology for studying gas-liquid mass transfer. J Chromatogr A; 2017 Jan 13;1480:83-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Another novelty of the present work is that the chromatographic sampling of the physicochemical phenomena is done without performing the usual flow reversals procedure.
  • Vinyl chloride monomer's (VCM) interaction with various composition liquid foods: orange juice, milk and olive oil was used as model system.
  • [MeSH-major] Chromatography, Gas / methods. Gases / analysis. Gases / chemistry
  • [MeSH-minor] Chemical Phenomena. Diffusion. Entropy. Hot Temperature. Molecular Weight. Reproducibility of Results. Solubility. Vinyl Chloride / chemistry

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  • [Copyright] Copyright © 2016 Elsevier B.V. All rights reserved.
  • (PMID = 27993392.001).
  • [ISSN] 1873-3778
  • [Journal-full-title] Journal of chromatography. A
  • [ISO-abbreviation] J Chromatogr A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Gases; WD06X94M2D / Vinyl Chloride
  • [Keywords] NOTNLM ; Diffusion coefficient (major topic) / Henry’s law constant (major topic) / Inverse gas chromatography (major topic) / Mass transfer (major topic) / Physicochemical measurements (major topic) / Vinyl chloride (major topic)
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8. Farner Budarz J, Turolla A, Piasecki AF, Bottero JY, Antonelli M, Wiesner MR: Influence of Aqueous Inorganic Anions on the Reactivity of Nanoparticles in TiO<sub>2</sub> Photocatalysis. Langmuir; 2017 Mar 21;33(11):2770-2779
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The influence of inorganic anions on the photoreactivity and aggregation of titanium dioxide nanoparticles (NPs) was assessed by dosing carbonate, chloride, nitrate, phosphate, and sulfate as potassium salts at multiple concentrations.
  • Aggregate size and fractal dimension were measured over time by laser diffraction, and the isoelectric point (IEP) as a function of anion and concentration was obtained by measuring EPM versus pH.
  • Phosphate, carbonate, and to a lesser extent, sulfate decreased the IEP of TiO<sub>2</sub> and stabilized NP suspensions owing to specific surface interactions, whereas this was not observed for nitrate and chloride.
  • Chloride and nitrate do not specifically interact with TiO<sub>2</sub>, and sulfate creates relatively weak interactions with the TiO<sub>2</sub> surface such that no decrease in photogenerated hole reactivity was observed.
  • Quenching rate constants for the reaction of hydroxyl radicals with each inorganic anion do not provide a comprehensive explanation for the magnitude of this decrease, which arises from the interplay of several physicochemical phenomena.
  • The impact of anion species on hydroxyl radical inhibition was as follows: carbonate > chloride > phosphate > nitrate > sulfate.

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  • (PMID = 28238264.001).
  • [ISSN] 1520-5827
  • [Journal-full-title] Langmuir : the ACS journal of surfaces and colloids
  • [ISO-abbreviation] Langmuir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Feitosa E, Karlsson G, Edwards K: Unilamellar vesicles obtained by simply mixing dioctadecyldimethylammonium chloride and bromide with water. Chem Phys Lipids; 2006 Apr;140(1-2):66-74
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  • [Title] Unilamellar vesicles obtained by simply mixing dioctadecyldimethylammonium chloride and bromide with water.
  • Optically clear dispersions of dioctadecyldimethylammonium bromide and chloride (DODAX, X = Br-, Cl-) in water can be obtained by simply mixing the amphiphiles at low concentrations (1 mM) and at a temperature safely above the gel to liquid crystalline phase transition temperature (Tm approximately 45-48 degrees C) of DODAX in water.
  • [MeSH-major] Membranes, Artificial. Quaternary Ammonium Compounds / chemistry
  • [MeSH-minor] Absorption. Chemistry, Physical. Light. Microscopy, Electron, Transmission / methods. Phase Transition. Physicochemical Phenomena. Scattering, Radiation. Sensitivity and Specificity. Temperature. Water / chemistry

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  • (PMID = 16494856.001).
  • [ISSN] 0009-3084
  • [Journal-full-title] Chemistry and physics of lipids
  • [ISO-abbreviation] Chem. Phys. Lipids
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Membranes, Artificial; 0 / Quaternary Ammonium Compounds; 059QF0KO0R / Water; 251IW5I21C / dimethyldioctadecylammonium
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10. Sah H: Protein behavior at the water/methylene chloride interface. J Pharm Sci; 1999 Dec;88(12):1320-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Protein behavior at the water/methylene chloride interface.
  • The objective of this study was to investigate the behaviors of proteins at the water/methylene chloride interface to better understand denaturing effects of emulsification upon proteins.
  • This study demonstrated that protein instability during emulsification was traced to consequences of the adsorption and conformational rearrangements of proteins at the water/methylene chloride interface.
  • [MeSH-major] Methylene Chloride / chemistry. Proteins / chemistry
  • [MeSH-minor] Chemistry, Physical. Chromatography, High Pressure Liquid. Electrophoresis, Polyacrylamide Gel. Physicochemical Phenomena. Protein Conformation. Ribonucleases / chemistry. Serum Albumin / chemistry. Solvents. Surface Properties. Water

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  • (PMID = 10585229.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Proteins; 0 / Serum Albumin; 0 / Solvents; 059QF0KO0R / Water; 588X2YUY0A / Methylene Chloride; EC 3.1.- / Ribonucleases
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11. Ramesh V, Shihabuddeen Syed A, Jagannathan K, Rajarajan K: Growth, spectroscopic and physicochemical properties of bis mercury ferric chloride tetra thiocyanate: a nonlinear optical crystal. Spectrochim Acta A Mol Biomol Spectrosc; 2013 May;108:236-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Growth, spectroscopic and physicochemical properties of bis mercury ferric chloride tetra thiocyanate: a nonlinear optical crystal.
  • Single crystal of bis mercury ferric chloride tetra thiocyanate [Hg2FeCl3(SCN)4; (MFCTC)] was grown from ethanol-water (3:1) mixed solvent using slow evaporation solvent technique (SEST) for the first time.
  • The coordination of transition metal ions with the SCN ligand is well-identified using FT-IR spectral analysis.
  • The ESR spectral profile of MFCTC was recorded from 298 K to 110K, which strongly suggests the incorporation of Fe(3+) ion and its environment with respect to SCN ligand.
  • [MeSH-major] Chlorides / chemistry. Ferric Compounds / chemistry. Mercury Compounds / chemistry. Nonlinear Dynamics. Optical Phenomena. Thiocyanates / chemistry

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  • [Copyright] Copyright © 2013 Elsevier B.V. All rights reserved.
  • (PMID = 23501934.001).
  • [ISSN] 1873-3557
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chlorides; 0 / Elements; 0 / Ferric Compounds; 0 / Mercury Compounds; 0 / Thiocyanates; U38V3ZVV3V / ferric chloride
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12. Garza-Ortiz A, den Dulk H, Brouwer J, Kooijman H, Spek AL, Reedijk J: The synthesis, chemical and biological properties of dichlorido(azpy)gold(III) chloride (azpy=2-(phenylazo)pyridine) and the gold-induced conversion of the azpy ligand to the chloride of the novel tricyclic pyrido[2,1-c][1,2,4]benzotriazin-11-ium cation. J Inorg Biochem; 2007 Nov;101(11-12):1922-30
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  • [Title] The synthesis, chemical and biological properties of dichlorido(azpy)gold(III) chloride (azpy=2-(phenylazo)pyridine) and the gold-induced conversion of the azpy ligand to the chloride of the novel tricyclic pyrido[2,1-c][1,2,4]benzotriazin-11-ium cation.
  • The chemical stability of the cation in this compound, [Au(azpy)Cl(2)](+) (abbreviated: Au-azpy), was analyzed by means of several physicochemical methods.
  • A cationic organic derivative of 2-(phenylazo)pyridine, (abbreviated: pyrium), was produced from the solution and has been isolated as its chloride salt and characterized by crystal structure determination, elemental analysis, NMR, ESI-MS and conductivity studies in solution.
  • The Au adduct and the pyrium cation were investigated as potential cytotoxic and anticancer agents, and both show moderate to high cytotoxic properties in cisplatin-sensitive and cisplatin-resistant ovarian carcinoma cell lines, A2780; and cisplatin-sensitive and cisplatin-resistant murine lymphocytic leukemia cell lines, L1210.
  • Significant anticancer activity against the cisplatin resistant cell lines was found for the pyrium salt, ruling out the occurrence of cross resistance phenomena.
  • [MeSH-major] Gold / chemistry. Organogold Compounds / chemical synthesis. Pyridines / chemistry

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  • (PMID = 17637477.001).
  • [ISSN] 0162-0134
  • [Journal-full-title] Journal of inorganic biochemistry
  • [ISO-abbreviation] J. Inorg. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organogold Compounds; 0 / Pyridines; 7440-57-5 / Gold; NH9L3PP67S / pyridine; Q20Q21Q62J / Cisplatin
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13. Dyke PH, Sutton M, Wood D, Marshall J: Investigations on the effect of chlorine in lubricating oil and the presence of a diesel oxidation catalyst on PCDD/F releases from an internal combustion engine. Chemosphere; 2007 Apr;67(7):1275-86
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  • [Title] Investigations on the effect of chlorine in lubricating oil and the presence of a diesel oxidation catalyst on PCDD/F releases from an internal combustion engine.
  • This paper reports on an intensive study into releases of polychlorinated dibenzo-p-dioxins (PCDD), polychlorinated furans (PCDF) and polychlorinated biphenyls (PCB) from a diesel engine and the analysis of PCDD/F and PCB in crankcase lubricating oil.
  • Experimental conditions were set and carefully controlled in order to maximize the possible impact of, and our ability to measure the effect of, changes in the levels of chlorine in the lubricant.
  • A series of 40 experimental runs were completed using three reference lubricants formulated to have three levels of chlorine present as a residual component (at levels of 12, 131 and 259 mg kg(-1) or ppm).
  • All lubricants were realistic oils and the use of unrealistic additives or doping of components - particularly chlorine - in the fuel and lubricant was carefully avoided.
  • The testing demonstrated the need for extreme care to be taken in developing measurement methods that are sufficiently sensitive for measuring chlorine content of fluids and PCDD/F in oils, the latter being particularly challenging.
  • The results of this testing showed that the emissions of PCDD/F were greatly reduced by the presence of a diesel oxidation catalyst in the exhaust, a finding that has not been explicitly tested in previous work.
  • They also show that emissions from the engine were not controlled by the level of chlorine in the lubricant and that emissions did not change in response to a much greater step change in the total chlorine entering the combustion chamber due to a change in the level of chlorine in the fuel.
  • [MeSH-major] Chlorine / analysis. Gasoline / analysis. Gasoline / toxicity. Industrial Oils / analysis. Industrial Oils / toxicity. Tetrachlorodibenzodioxin / analogs & derivatives. Vehicle Emissions / analysis
  • [MeSH-minor] Catalysis. Chemistry, Physical. Chromatography, Ion Exchange. Dioxins / analysis. Environmental Pollutants / analysis. Gas Chromatography-Mass Spectrometry. Lubrication. Neutron Activation Analysis. Oxidation-Reduction. Physicochemical Phenomena. Polychlorinated Biphenyls / analysis. Quality Control

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  • (PMID = 17254630.001).
  • [ISSN] 0045-6535
  • [Journal-full-title] Chemosphere
  • [ISO-abbreviation] Chemosphere
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dioxins; 0 / Environmental Pollutants; 0 / Gasoline; 0 / Vehicle Emissions; 0 / polychlorodibenzo-4-dioxin; 4R7X1O2820 / Chlorine; DFC2HB4I0K / Polychlorinated Biphenyls; DO80M48B6O / Tetrachlorodibenzodioxin
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14. Snejdrová E, Zelenka J, Rehula M: [Effect of sodium chloride on elasticity of silicone matrices]. Ceska Slov Farm; 2002 Sep;51(5):248-51
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect of sodium chloride on elasticity of silicone matrices].
  • An increase in the availability of the active ingredient from silicone matrices can be achieved by using sodium chloride as the filler.
  • An addition of sodium chloride also influences the mechanical properties of silicone systems.
  • The temperature dependence of real Young's model E' of addition silicone systems with sodium chloride was measured.
  • The effect of chloride is best described by the relation proposed by Nielsen.
  • Hydrodynamic theory provides good results for sodium chloride particle size of 102.5 microns, but for particle sizes of 20 microns and 60 microns it is less successful than Nielsen's relation.
  • [MeSH-major] Pharmaceutical Vehicles. Silicone Elastomers. Sodium Chloride
  • [MeSH-minor] Chemistry, Pharmaceutical. Chemistry, Physical. Elasticity. Physicochemical Phenomena

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  • (PMID = 12407924.001).
  • [ISSN] 1210-7816
  • [Journal-full-title] Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti
  • [ISO-abbreviation] Ceska Slov Farm
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Pharmaceutical Vehicles; 0 / Silicone Elastomers; 451W47IQ8X / Sodium Chloride
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15. Neef C, Meijer DK: Structure-pharmacokinetics relationship of quaternary ammonium compounds. Correlation of physicochemical and pharmacokinetic parameters. Naunyn Schmiedebergs Arch Pharmacol; 1984 Dec;328(2):111-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Structure-pharmacokinetics relationship of quaternary ammonium compounds. Correlation of physicochemical and pharmacokinetic parameters.
  • Correlations between lipophilicity or molecular weight and some pharmacokinetic parameters such as clearance (Cl), elimination rate constant (k10), volume of distribution (V), and terminal half life (lambda z) are presented for a series of structurally related quaternary ammonium cations (QACs).
  • The relationship between total plasma clearance or hepatic, renal and intestinal clearance and lipophilicity for the present set of data could be described most properly by the equation Y = 1/(aXb + c), where Y stands for the logarithm of the pharmacokinetic parameters and X represents the logarithm of the values of some physicochemical parameters, such as the partition coefficient (P), the (HPLC) capacity factor k' (another lipophilicity parameter) and molecular weight (MW).
  • The extent of biliary output of the organic cations shows a threshold phenomenon, sharply increasing at log P greater than 1.5 to a maximum at P greater than 2.5.
  • [MeSH-minor] Animals. Chemistry, Physical. Half-Life. Intestines / metabolism. Kidney / metabolism. Kinetics. Lipids / analysis. Liver / metabolism. Male. Molecular Weight. Physicochemical Phenomena. Protein Binding. Rats. Solubility. Structure-Activity Relationship

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  • (PMID = 6527701.001).
  • [ISSN] 0028-1298
  • [Journal-full-title] Naunyn-Schmiedeberg's archives of pharmacology
  • [ISO-abbreviation] Naunyn Schmiedebergs Arch. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] GERMANY, WEST
  • [Chemical-registry-number] 0 / Lipids; 0 / Quaternary Ammonium Compounds
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16. Shemanova GF, Petrov RV, Dmitrieva LN, Panteleev EI, Drachev VA: [Homogeneous Cl. perfringens alpha-anatoxin: its physicochemical and immunogenic properties]. Zh Mikrobiol Epidemiol Immunobiol; 1978 May;(5):117-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Homogeneous Cl. perfringens alpha-anatoxin: its physicochemical and immunogenic properties].
  • [Transliterated title] Gomogennyĭ al'fa-anatoksin C1. perfringens: ego fiziko-khimicheskie i immunogennye svoĭstva.
  • The authors present a method of obtaining relatively homogeneous preparations of alpha-toxoid of Cl. perfringens, type A, including the primary conception of the alpha-toxin proteins, their chromatography on DEAE-cellulose, fractionation with (NH4)2SO4, detoxication, with the subsequent gel-filtration through sephadex and isoelectric focussing.
  • [MeSH-minor] Animals. Chemistry, Physical. Electrophoresis, Polyacrylamide Gel. Guinea Pigs. Immunization. Immunization, Secondary. Isoelectric Focusing. Mice. Mice, Inbred C57BL. Mice, Inbred CBA. Physicochemical Phenomena. Rabbits. Time Factors

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  • (PMID = 208330.001).
  • [ISSN] 0372-9311
  • [Journal-full-title] Zhurnal mikrobiologii, epidemiologii, i immunobiologii
  • [ISO-abbreviation] Zh. Mikrobiol. Epidemiol. Immunobiol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] 0 / Toxoids
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17. Gaudreault J, Varin F, Pollack GM: Pharmacokinetics and anticonvulsant effect of a new hypnotic, CL 284,846, in rats. Pharm Res; 1995 Nov;12(11):1592-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacokinetics and anticonvulsant effect of a new hypnotic, CL 284,846, in rats.
  • PURPOSE: CL 284,846 (CL846) is an investigational non-benzodiazepine agent with hypnotic, anxiolytic, myorelaxant and anticonvulsant properties.
  • CL846 and the derived metabolite CL 284,859 (CL859) concentrations in serum and brain tissue were determined by HPLC with fluorescence detection.
  • [MeSH-minor] Animals. Biotransformation. Brain / metabolism. Chemistry, Physical. Female. Infusions, Intravenous. Pentylenetetrazole / antagonists & inhibitors. Physicochemical Phenomena. Rats. Rats, Sprague-Dawley. Solubility. Structure-Activity Relationship

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  • (PMID = 8592655.001).
  • [ISSN] 0724-8741
  • [Journal-full-title] Pharmaceutical research
  • [ISO-abbreviation] Pharm. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Acetamides; 0 / Anticonvulsants; 0 / Hypnotics and Sedatives; 0 / Pyrimidines; 151319-34-5 / zaleplon; WM5Z385K7T / Pentylenetetrazole
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18. Gough BM, Whitehouse ME, Greenwood CT: The role and function of chlorine in the preparation of high-ratio cake flour. CRC Crit Rev Food Sci Nutr; 1978;10(1):91-113
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role and function of chlorine in the preparation of high-ratio cake flour.
  • The literature on the role of chlorine treatment of flour for use in high-ratio cake production is discussed in relation to current knowledge of cereal chemistry and cake technology.
  • A brief perspective of the present use of chlorine in high-ratio cake flours is included.
  • Investigations of the uptake of gaseous chlorine by flour and its distribution among and chemical action upon the major flour components (water, protein, lipid, and carbohydrate) are assessed.
  • The physical effects of chlorination as demonstrated by experiments with batters and cakes and by physicochemical observations of flour and its fractions are also considered.
  • The characteristics of the starch in flour appear to be critical in high-ratio cakes.
  • Chlorine treatment modifies the gelatinization behavior of the starch granules yet does not change their gelatinization temperature not is there evidence of chemical attack upon the starch molecules.
  • Therefore, it is suggested that chlorine effects the necessary changes in starch behavior by reacting with the noncarbohydrate surface contaminants on the granules.
  • [MeSH-major] Chlorine. Flour. Triticum
  • [MeSH-minor] Chemical Phenomena. Chemistry. Cooking / standards. Fats. Food Technology. Hot Temperature. Hydrogen-Ion Concentration. Polysaccharides. Starch. Viscosity. Zea mays

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  • (PMID = 31265.001).
  • [ISSN] 0099-0248
  • [Journal-full-title] CRC critical reviews in food science and nutrition
  • [ISO-abbreviation] CRC Crit Rev Food Sci Nutr
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Fats; 0 / Polysaccharides; 4R7X1O2820 / Chlorine; 9005-25-8 / Starch
  • [Number-of-references] 92
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19. Hellauer H, Winkler R: Denaturation of collagen fibers in NaI, NaCl and water of different pH values as studied by differential scanning calorimetric measurements. Connect Tissue Res; 1975;3(4):227-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Denaturation of collagen fibers in NaI, NaCl and water of different pH values as studied by differential scanning calorimetric measurements.
  • Microcalorimetric measurements of rat tail tendon collagen in different aqueous media show the following behavior of denaturation temperature (Td) and of denaturation enthalpy (deltaHd): H+ and OH- ions lower Td significantly beyond pH 4...11.
  • Addition of salts (0.15 M) generally lowers Td in the range between pH 5 and 10, I- being more effective than Cl- at pH greater than i.p.
  • However, in the region of pH less than i.p., I- raises Td to values above those of Cl- and even those of water.
  • The value of deltaHd was found to be insensitive to pH over the pH range of 4...11.
  • [MeSH-major] Collagen. Iodides. Sodium Chloride
  • [MeSH-minor] Animals. Calorimetry. Chemistry, Physical. Chlorides. Female. Hydrogen-Ion Concentration. Physicochemical Phenomena. Protein Denaturation. Rats. Temperature

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  • (PMID = 240647.001).
  • [ISSN] 0300-8207
  • [Journal-full-title] Connective tissue research
  • [ISO-abbreviation] Connect. Tissue Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Chlorides; 0 / Iodides; 451W47IQ8X / Sodium Chloride; 9007-34-5 / Collagen
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20. Pouliquen D, Gallois Y: Physicochemical properties of structured water in human albumin and gammaglobulin solutions. Biochimie; 2001 Sep;83(9):891-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical properties of structured water in human albumin and gammaglobulin solutions.
  • The physicochemical properties of the different phases of water molecules were studied in concentrated solutions (132 g/L) of human serum albumin and gammaglobulin by (1)H NMR relaxometry.
  • Comparison of the temperature dependence of the structured water's T1 in the two solutions in the presence of an increasing concentration of manganese chloride allowed two main conclusions to be drawn.
  • Firstly, the differences observed in total water and structured water physicochemical properties are directly related to protein structure and three-dimensional arrangement.
  • [MeSH-major] Albumins / chemistry. Water / chemistry. gamma-Globulins / chemistry
  • [MeSH-minor] Chemistry, Physical. Electron Spin Resonance Spectroscopy. Humans. Magnetic Resonance Spectroscopy. Physicochemical Phenomena. Solutions / chemistry. Spin Trapping. Temperature

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  • (PMID = 11698111.001).
  • [ISSN] 0300-9084
  • [Journal-full-title] Biochimie
  • [ISO-abbreviation] Biochimie
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Albumins; 0 / Solutions; 0 / gamma-Globulins; 059QF0KO0R / Water
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21. Berth G, Dautzenberg H, Christensen BE, Rother G, Smidsrød O: Physicochemical studies on xylinan (acetan). I. Characterization by gel permeation chromatography on sepharose Cl-2B coupled with static light scattering and viscometry. Biopolymers; 1996 Nov;39(5):709-19

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical studies on xylinan (acetan). I. Characterization by gel permeation chromatography on sepharose Cl-2B coupled with static light scattering and viscometry.
  • Laboratory-made samples of the polysaccharide xylinan (acetan) were fractionated on Sepharose Cl-2B using 0.1M NaCl as eluant.
  • The experimental data is found to be consistent with a persistence length of Lp = 100 nm.
  • Our results suggest a fractionation according to the contour length rather than the molar mass.
  • [MeSH-major] Polysaccharides, Bacterial / chemistry
  • [MeSH-minor] Acetobacter / chemistry. Biopolymers / chemistry. Carbohydrate Sequence. Chemistry, Physical. Chromatography, Agarose. Light. Molecular Sequence Data. Physicochemical Phenomena. Scattering, Radiation. Viscosity

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  • (PMID = 8875824.001).
  • [ISSN] 0006-3525
  • [Journal-full-title] Biopolymers
  • [ISO-abbreviation] Biopolymers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Biopolymers; 0 / Polysaccharides, Bacterial; 107853-49-6 / xylinan
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22. Wedekind D, Schweitzer-Stenner R, Dreybrodt W: Heme-apoprotein interaction in the modified oxyhemoglobin-bis(N-maleimidomethyl)ether and in oxyhemoglobin at high Cl-concentration detected by resonance Raman scattering. Biochim Biophys Acta; 1985 Aug 23;830(3):224-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Heme-apoprotein interaction in the modified oxyhemoglobin-bis(N-maleimidomethyl)ether and in oxyhemoglobin at high Cl-concentration detected by resonance Raman scattering.
  • The dispersion of the depolarization ratio of oxidation and spin-marker lines of oxyhemoglobin-bis(N-maleimidomethyl)ether and oxyhemoglobin at high Cl- concentration (1 M) have been examined for different pH values in the neutral and alkaline regions.
  • The oxidation marker line at 1375 cm-1 shows no pH-dependence in the physiological region for oxyHb-bis(N-maleimidomethyl)ether and a comparatively small variation for oxyHb at a Cl- concentration higher than 0.4 M.
  • The spin-marker line at 1638 cm-1 exhibits a strong pH-dependence of depolarization ratio for high Cl- concentration, but a minor pH-induced variation for oxyHb-bis(N-maleimidomethyl)ether.
  • (1) The oxidation marker line monitors symmetry-lowering distortions of the heme group introduced by central coupling to the protein via the Fe-N bond, whereas the spin-marker line monitors peripheral coupling due to heme-protein interaction in the heme pocket. (2) At low Cl- concentrations (below 0.3 M) both types of coupling are present.
  • These are induced by the salt bridge between His 146 beta and Asp94 beta and flexibility of the FG corner. (3) At high Cl- concentrations the salt bridge is missing, eliminating central coupling. (4) In oxyhemoglobin-bis(N-maleimidomethyl)ether, due to constraint of the bis(N-maleimidomethyl)ether bridging the FG corner and eliminating its flexibility and the missing salt bridge, both central and peripheral coupling are drastically reduced.
  • [MeSH-minor] Adult. Chemistry, Physical. Humans. Hydrogen-Ion Concentration. Oxidation-Reduction. Physicochemical Phenomena. Spectrum Analysis, Raman

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  • (PMID = 4027250.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Apoproteins; 0 / Chlorides; 0 / Oxyhemoglobins; 42VZT0U6YR / Heme
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23. Gaizer SN, Pintye-Hódi K, Selmeczi B: Release kinetics of potassium aspartate in polyvinyl chloride matrix formulation. Pharmazie; 1987 Jul;42(7):463-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Release kinetics of potassium aspartate in polyvinyl chloride matrix formulation.
  • The authors prepared potassium aspartate matrix tablets in combination with polyvinyl chloride.
  • The physical parameters were measured and the dissolution rates were determined.
  • [MeSH-minor] Chemistry, Physical. Diffusion. Particle Size. Physicochemical Phenomena. Polyvinyl Chloride. Solubility. Tablets, Enteric-Coated

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  • (PMID = 3671474.001).
  • [ISSN] 0031-7144
  • [Journal-full-title] Die Pharmazie
  • [ISO-abbreviation] Pharmazie
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] GERMANY, EAST
  • [Chemical-registry-number] 0 / Tablets, Enteric-Coated; 30KYC7MIAI / Aspartic Acid; 9002-86-2 / Polyvinyl Chloride
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24. Nestor I, Lazăr L: [Microbiological and physicochemical indicators of viral contamination of the drinking water]. Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol; 1989 Jul-Sep;34(3):207-24
MedlinePlus Health Information. consumer health - Water Pollution.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Microbiological and physicochemical indicators of viral contamination of the drinking water].
  • [Transliterated title] Indicatorii microbiologici şi fizico-chimici ai contaminării virale a apei de băut.
  • An analysis is made of: physico-chemical indicators (water turbidity, residual chlorine, some products of the bacterial metabolism in the intestine), bacterial indicators (total and faecal coliforms, Escherichia coli, faecal streptococci, clostridia and other intestinal anaerobic bacteria, saprophytic mycobacteria, Pseudomonas aeruginosa) and some bacteriophages.
  • [MeSH-minor] Bacteria / isolation & purification. Bacteriophages / isolation & purification. Chemistry, Physical. Colony Count, Microbial. Feces / microbiology. Humans. Physicochemical Phenomena

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  • (PMID = 2694300.001).
  • [ISSN] 0376-4494
  • [Journal-full-title] Revista de igienă, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Bacteriologia, virusologia, parazitologia, epidemiologia
  • [ISO-abbreviation] Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] ROMANIA
  • [Number-of-references] 127
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25. Roughley PJ, Hatt M, Mason RM: Physicochemical properties of cartilage proteoglycans extracted by lanthanum chloride. Biochim Biophys Acta; 1978 Apr 3;539(4):445-58
Hazardous Substances Data Bank. CALCIUM CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical properties of cartilage proteoglycans extracted by lanthanum chloride.
  • The properties of PLaCl3 were investigated by chemical analysis, electrophoresis, viscometry and analytical ultracentrifugation, and the results compared with those for proteoglycan obtained by caesium chloride density gradient centrifugation of 2 M CaCl2 cartilage extracts.
  • [MeSH-minor] Animals. Calcium Chloride. Cattle. Chemistry, Physical. Chlorides. Hydrogen-Ion Concentration. Nose. Physicochemical Phenomena. Viscosity

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  • (PMID = 25090.001).
  • [ISSN] 0006-3002
  • [Journal-full-title] Biochimica et biophysica acta
  • [ISO-abbreviation] Biochim. Biophys. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Chlorides; 0 / Proteoglycans; 6I3K30563S / Lanthanum; M4I0D6VV5M / Calcium Chloride
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26. Do VT, Tang CY, Reinhard M, Leckie JO: Effects of chlorine exposure conditions on physiochemical properties and performance of a polyamide membrane--mechanisms and implications. Environ Sci Technol; 2012 Dec 18;46(24):13184-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of chlorine exposure conditions on physiochemical properties and performance of a polyamide membrane--mechanisms and implications.
  • Understanding the effects of chlorine exposure on polyamide (PA) based membranes is essential in membrane lifespan improvement.
  • The changes in membrane elemental composition and bonding chemistry obtained from XPS and ATR-FTIR revealed the impacts of two competing mechanisms: N-chlorination and chlorination-promoted hydrolysis.
  • More chlorine was incorporated into the PA matrix at pH <7, at which HOCl is dominant, while chlorine-promoted hydrolysis was more favorable at pH >7 with abundant hydroxyl groups.
  • However, when hydrolysis was severe (≥ 1000 ppm, pH 7 and 9), the enhanced charge repulsion effect could not compensate for the extensive amide bond cleavage, resulting in declined rejection.
  • [MeSH-major] Chlorine / chemistry. Membranes, Artificial. Nylons / chemistry. Physicochemical Phenomena
  • [MeSH-minor] Calcium / chemistry. Cations. Filtration. Halogenation. Hydrogen-Ion Concentration. Hydrolysis. Nanotechnology. Nitrogen / analysis. Oxygen / analysis. Permeability. Sodium Chloride / chemistry. Spectroscopy, Fourier Transform Infrared. Surface Properties. Time Factors. Water / chemistry. Water Pollutants, Chemical / analysis

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  • (PMID = 23214945.001).
  • [ISSN] 1520-5851
  • [Journal-full-title] Environmental science & technology
  • [ISO-abbreviation] Environ. Sci. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cations; 0 / Membranes, Artificial; 0 / Nylons; 0 / Water Pollutants, Chemical; 059QF0KO0R / Water; 451W47IQ8X / Sodium Chloride; 4R7X1O2820 / Chlorine; N762921K75 / Nitrogen; S88TT14065 / Oxygen; SY7Q814VUP / Calcium
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27. Subová M, Vitková Z, Cirbusová E, Erös I, Kónya M: [Effect of polymer concentration on rheological properties of Carbopol 980 hydrogels containing trimecainium chloride]. Ceska Slov Farm; 2005 Mar;54(2):96-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect of polymer concentration on rheological properties of Carbopol 980 hydrogels containing trimecainium chloride].
  • The present paper examines the effect of Carbopol 980 concentration on rheological properties of hydrogels with and without trimecainium chloride for a period of 2, 7, and 14 days after their preparation.
  • On the basis of an evaluation of the changes in structural viscosity in dependence on the period of measurement, it has been concluded that for formulation of trimecainium chloride to a dermal dosage form, Carbopol 980 concentrations of 0.5 and 1.2 % are suitable.
  • [MeSH-major] Acrylic Resins / chemistry. Anesthetics, Local. Hydrogels / chemistry. Trimecaine
  • [MeSH-minor] Chemistry, Physical. Physicochemical Phenomena. Rheology

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  • (PMID = 15895974.001).
  • [ISSN] 1210-7816
  • [Journal-full-title] Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti
  • [ISO-abbreviation] Ceska Slov Farm
  • [Language] slo
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Acrylic Resins; 0 / Anesthetics, Local; 0 / Hydrogels; 0 / carbomer; IN1233R0JO / Trimecaine
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28. Mizoguchi A, Ohshima Y, Endo Y: Microscopic hydration of the sodium chloride ion pair. J Am Chem Soc; 2003 Feb 19;125(7):1716-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microscopic hydration of the sodium chloride ion pair.
  • Hydration of ion pairs is an essential process in various physicochemical phenomena occurring in solutions.
  • Isolated clusters of an ion pair solvated with finite number of waters have been considered as a model system for the critical evaluation of microscopic interactions involved in the process, and theoretical studies have contributed exclusively to the subject up to now.
  • Here we report the first experimental characterization of structure and internal dynamics of hydrated ion pairs, NaCl-(H2O)n (n = 1-3).
  • The measurements of their rotational spectra have proven that the clusters have cyclic forms, in which Na+ and Cl- ions are strongly interacted with the O and H atoms of the solvent molecules, respectively.
  • The Na-Cl distance shows a pronounced increase with the successive addition of water molecules.
  • The separation for n = 3 approaches the value predicted for the contact ion-pair state in aqueous solution by recent molecular dynamics simulations.
  • [MeSH-major] Sodium Chloride / chemistry. Water / chemistry

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  • (PMID = 12580594.001).
  • [ISSN] 0002-7863
  • [Journal-full-title] Journal of the American Chemical Society
  • [ISO-abbreviation] J. Am. Chem. Soc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anions; 0 / Cations, Monovalent; 0 / Solutions; 059QF0KO0R / Water; 451W47IQ8X / Sodium Chloride
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29. Keowmaneechai E, McClements DJ: Influence of EDTA and citrate on physicochemical properties of whey protein-stabilized oil-in-water emulsions containing CaCl2. J Agric Food Chem; 2002 Nov 20;50(24):7145-53
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of EDTA and citrate on physicochemical properties of whey protein-stabilized oil-in-water emulsions containing CaCl2.
  • The influence of chelating agents (disodium ethylenediaminetetraacetate (EDTA) and sodium citrate) on the physicochemical properties of whey protein isolate (WPI)-stabilized oil-in-water emulsions containing calcium chloride was determined.
  • The calcium-binding characteristics of EDTA and citrate at 30 degrees C were characterized in aqueous solutions (20 mM Tris buffer, pH 7.0) by isothermal titration calorimetry (ITC).
  • EDTA and citrate both bound calcium ions in a 1:1 ratio, but EDTA had a much higher binding constant.
  • Oil-in-water emulsions (pH 7.0) were prepared containing 6.94% (w/v) soybean oil, 0.35% (w/v) WPI, 0.02% (w/v) sodium azide, 20 mM Tris buffer, 10 mM CaCl(2), and 0-40 mM chelating agent.
  • Emulsions containing chelating agents had lower free calcium concentrations and more negatively charged droplets, indicating that the chelating agents improved emulsion stability by binding calcium ions.
  • EDTA could be used at lower concentrations than citrate because of its higher calcium ion binding constant.
  • [MeSH-major] Calcium Chloride / chemistry. Chelating Agents / pharmacology. Citric Acid / pharmacology. Edetic Acid / pharmacology. Emulsions / chemistry. Milk Proteins / chemistry
  • [MeSH-minor] Chemistry, Physical. Drug Stability. Electrochemistry. Hydrogen-Ion Concentration. Particle Size. Physicochemical Phenomena. Rheology. Sodium Azide. Solutions. Soybean Oil / chemistry. Viscosity. Water. Whey Proteins

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM CHLORIDE .
  • Hazardous Substances Data Bank. Disodium EDTA .
  • Hazardous Substances Data Bank. SODIUM AZIDE .
  • Hazardous Substances Data Bank. ETHYLENEDIAMINE TETRAACETIC ACID .
  • Hazardous Substances Data Bank. DISODIUM CALCIUM EDTA .
  • Hazardous Substances Data Bank. CITRIC ACID .
  • Hazardous Substances Data Bank. Water .
  • Hazardous Substances Data Bank. Soybean oil .
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  • (PMID = 12428974.001).
  • [ISSN] 0021-8561
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chelating Agents; 0 / Emulsions; 0 / Milk Proteins; 0 / Solutions; 0 / Whey Proteins; 059QF0KO0R / Water; 2968PHW8QP / Citric Acid; 8001-22-7 / Soybean Oil; 968JJ8C9DV / Sodium Azide; 9G34HU7RV0 / Edetic Acid; M4I0D6VV5M / Calcium Chloride
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30. Shimono K, Kitami M, Iwamoto M, Kamo N: Involvement of two groups in reversal of the bathochromic shift of pharaonis phoborhodopsin by chloride at low pH. Biophys Chem; 2000 Oct 30;87(2-3):225-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Involvement of two groups in reversal of the bathochromic shift of pharaonis phoborhodopsin by chloride at low pH.
  • Its lambdamax is at 496 nm, but upon acidification in the absence of chloride, lambdamax shifted to 522 nm.
  • In the presence of chloride, the spectral shifts were different: with a decrease in pH, a bathochromic shift was first observed, followed by a hypsochromic shift on further acidification.
  • This was interpreted as: the disappearance of a negative charge by the protonation of Asp75 was compensated by the binding of chloride, but it is worthy to note that the binding requires the protonation of another proton-associable group other than Asp75.
  • This is supported by the observation that in the presence of chloride, upon acidification, the lambdamax of D75N even showed a blue shift, showing that the protonation of a proton-associable group (pKa = 1.2) leads to the chloride binding that gives rise to a blue shift.
  • [MeSH-major] Archaeal Proteins. Bacteriorhodopsins / chemistry. Carotenoids. Halorhodopsins. Sensory Rhodopsins
  • [MeSH-minor] Chemistry, Physical. Chlorides / chemistry. Hydrogen-Ion Concentration. Natronobacterium / chemistry. Natronobacterium / genetics. Physicochemical Phenomena. Point Mutation. Recombinant Proteins / chemistry. Recombinant Proteins / genetics. Spectrophotometry

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  • (PMID = 11099184.001).
  • [ISSN] 0301-4622
  • [Journal-full-title] Biophysical chemistry
  • [ISO-abbreviation] Biophys. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Archaeal Proteins; 0 / Chlorides; 0 / Halorhodopsins; 0 / Recombinant Proteins; 0 / Sensory Rhodopsins; 0 / sensory rhodopsin II protein, archaeal; 36-88-4 / Carotenoids; 53026-44-1 / Bacteriorhodopsins
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31. Glisson BT, Craft BF, Nelson JH, Meuzelaar HL: Production of vinylidene chloride from the thermal decomposition of methyl chloroform. Am Ind Hyg Assoc J; 1986 Jul;47(7):427-35
Hazardous Substances Data Bank. 1,1-DICHLOROETHYLENE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Production of vinylidene chloride from the thermal decomposition of methyl chloroform.
  • This study investigated the extent to which methyl chloroform undergoes thermal decomposition to form vinylidene chloride.
  • Vinylidene chloride was detected in nearly stoichiometric amounts.
  • Once again, the conversion to vinylidene chloride was nearly complete.
  • First, under these experimental conditions, methyl chloroform undergoes thermal decomposition to yield substantial quantities of vinylidene chloride.
  • [MeSH-minor] Chemistry, Physical. Copper. Gas Chromatography-Mass Spectrometry. Glass. Physicochemical Phenomena. Temperature

  • Hazardous Substances Data Bank. 1,1,1-TRICHLOROETHANE .
  • Hazardous Substances Data Bank. COPPER, ELEMENTAL .
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  • [ErratumIn] Am Ind Hyg Assoc J 1986 Oct;47(10):665
  • (PMID = 3751891.001).
  • [ISSN] 0002-8894
  • [Journal-full-title] American Industrial Hygiene Association journal
  • [ISO-abbreviation] Am Ind Hyg Assoc J
  • [Language] eng
  • [Grant] United States / NIOSH CDC HHS / OH / 5-T15-OH07141-06
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Dichloroethylenes; 0 / Hydrocarbons, Chlorinated; 0 / Trichloroethanes; 113C650IR1 / 1,1,1-trichloroethane; 21SK105J9D / vinylidene chloride; 789U1901C5 / Copper
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32. Bellon SF, Lippard SJ: Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3)2(N3-cytosine)Cl]+. Biophys Chem; 1990 Apr;35(2-3):179-88
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3)2(N3-cytosine)Cl]+.
  • Duplex oligonucleotides containing a single intrastrand [Pt(NH3)2]2+ cross-link or monofunctional adduct and either 15 or 22 bp in length were synthesized and chemically characterized.
  • When modified by the monofunctional adduct cis-[Pt(NH3)2(N3-cytosine)(dG)]Cl the helix remains rod-like.
  • [MeSH-minor] Autoradiography. Base Sequence. Chemistry, Physical. Hydrolysis. Molecular Conformation. Molecular Sequence Data. Physicochemical Phenomena. Spectrophotometry, Atomic. Stereoisomerism

  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
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  • (PMID = 2397272.001).
  • [ISSN] 0301-4622
  • [Journal-full-title] Biophysical chemistry
  • [ISO-abbreviation] Biophys. Chem.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA34992
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; 9007-49-2 / DNA; Q20Q21Q62J / Cisplatin
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33. Choi YM, Jung KC, Jo HM, Nam KW, Choe JH, Rhee MS, Kim BC: Combined effects of potassium lactate and calcium ascorbate as sodium chloride substitutes on the physicochemical and sensory characteristics of low-sodium frankfurter sausage. Meat Sci; 2014 Jan;96(1):21-5
Hazardous Substances Data Bank. SODIUM CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined effects of potassium lactate and calcium ascorbate as sodium chloride substitutes on the physicochemical and sensory characteristics of low-sodium frankfurter sausage.
  • The purpose of this study was to evaluate the combined effects of sodium chloride (NaCl) substitutes, including potassium lactate (K-lactate) and calcium ascorbate (Ca-ascorbate), on the physicochemical and sensory characteristics of low-sodium frankfurter sausage (1.2% content of NaCl).
  • [MeSH-major] Ascorbic Acid / analysis. Color. Meat Products / analysis. Potassium / analysis. Sodium Chloride / analysis. Taste
  • [MeSH-minor] Adult. Animals. Female. Food Additives / analysis. Food Handling. Humans. Hydrogen-Ion Concentration. Lactic Acid / analysis. Linear Models. Male. Physicochemical Phenomena. Swine. Young Adult

  • MedlinePlus Health Information. consumer health - Potassium.
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  • Hazardous Substances Data Bank. Sodium ascorbate .
  • Hazardous Substances Data Bank. LACTIC ACID .
  • Hazardous Substances Data Bank. L-Ascorbic Acid .
  • Hazardous Substances Data Bank. CALCIUM ASCORBATE .
  • Hazardous Substances Data Bank. POTASSIUM, ELEMENTAL .
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  • [Copyright] Copyright © 2013 Elsevier Ltd. All rights reserved.
  • (PMID = 23896133.001).
  • [ISSN] 1873-4138
  • [Journal-full-title] Meat science
  • [ISO-abbreviation] Meat Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Food Additives; 183E4W213W / calcium ascorbate; 33X04XA5AT / Lactic Acid; 451W47IQ8X / Sodium Chloride; PQ6CK8PD0R / Ascorbic Acid; RWP5GA015D / Potassium
  • [Keywords] NOTNLM ; Calcium ascorbate / Frankfurter / Physicochemical and sensory quality / Potassium lactate / Sodium chloride substitute
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34. Pavagadhi S, Tang AL, Sathishkumar M, Loh KP, Balasubramanian R: Removal of microcystin-LR and microcystin-RR by graphene oxide: adsorption and kinetic experiments. Water Res; 2013 Sep 1;47(13):4621-9
Hazardous Substances Data Bank. GRAPHITE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The environmental pollutants addressed in this study included different anions (nitrate NO3-, nitrite NO2-, sulphate SO4(2-), chloride (Cl(-)), phosphate PO4(3-) and fluoride (F(-))) and cations (sodium (Na(+)), potassium (K(+)), magnesium (Mg(2+)) and calcium (Ca(2+))).
  • [MeSH-major] Graphite / chemistry. Microcystins / isolation & purification. Oxides / chemistry
  • [MeSH-minor] Adsorption. Anions / chemistry. Cations / chemistry. Charcoal / chemistry. Environment. Hydrogen-Ion Concentration. Kinetics. Microscopy, Atomic Force. Photoelectron Spectroscopy. Physicochemical Phenomena. Singapore

  • Hazardous Substances Data Bank. Microcystin-LR .
  • Hazardous Substances Data Bank. ACTIVATED CHARCOAL .
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  • [Copyright] Copyright © 2013 Elsevier Ltd. All rights reserved.
  • (PMID = 23764611.001).
  • [ISSN] 1879-2448
  • [Journal-full-title] Water research
  • [ISO-abbreviation] Water Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anions; 0 / Cations; 0 / Microcystins; 0 / Oxides; 101043-37-2 / cyanoginosin LR; 111755-37-4 / microcystin RR; 16291-96-6 / Charcoal; 7782-42-5 / Graphite
  • [Keywords] NOTNLM ; Adsorption / Algal bloom / Cyanotoxin / Graphene oxide / MCLR / MCRR / Microcystin
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35. Faccia M, Mastromatteo M, Conte A, Del Nobile MA: Influence of the different sodium chloride concentrations on microbiological and physico-chemical characteristics of mozzarella cheese. J Dairy Res; 2012 Nov;79(4):390-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of the different sodium chloride concentrations on microbiological and physico-chemical characteristics of mozzarella cheese.
  • In this work the effects of addition of different amounts of sodium chloride, during cheese making, on shelf life of mozzarella cheese were evaluated.
  • The mozzarella cheese quality decay was assessed during storage at 9 °C by monitoring microbiological, sensory and physico-chemical changes in the product.
  • Results showed that Pseudomonas spp. growth was responsible for cheese unacceptability, whereas the sensory quality did not limit cheese shelf life.
  • On the contrary, high salt concentrations affected product shelf life, probably as a consequence of progressive solubilisation of cheese casein, due to the phenomenon of 'salting in'.
  • [MeSH-major] Cheese / analysis. Cheese / microbiology. Sodium Chloride / administration & dosage
  • [MeSH-minor] Dose-Response Relationship, Drug. Food Quality. Food Storage. Humans. Hydrogen-Ion Concentration. Odors. Physicochemical Phenomena. Pseudomonas / growth & development. Sensation. Time Factors

  • Hazardous Substances Data Bank. SODIUM CHLORIDE .
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  • (PMID = 22874075.001).
  • [ISSN] 1469-7629
  • [Journal-full-title] The Journal of dairy research
  • [ISO-abbreviation] J. Dairy Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
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36. Kopecký F, Kopecká B, Kaclík P: [Properties of benzethonium chloride in micellar solutions and the effect of added sodium chloride]. Ceska Slov Farm; 2006 Jul;55(4):175-80
Hazardous Substances Data Bank. SODIUM CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Properties of benzethonium chloride in micellar solutions and the effect of added sodium chloride].
  • Aqueous solutions of the antimicrobially effective quaternary ammonium salt benzethonium chloride (hyamine 1622) were studied using UV spectrophotometry and partially conductometry.
  • The spectra of micellar solutions of benzethonium chloride revealed a concentration-dependent bathochromic and hyperchromic shift of a weak UV absorption band in the region 250-300 nm.
  • This served to elaborate the spectrophotometric determination of the critical micellar concentration (CMC) of benzethonium chloride and the concentration of free benzethonium cations in micellar solutions without an addition of NaCl and with a constant addition of NaCl 0.003, 0.1 and 0.15 mol/l.
  • Premicellar associations were not observed and in NaCl-free solutions CMC 0.0028 mol/l was spectrophotometrically determined.
  • The courses of the determined concentrations of free benzethonium cations in the solutions both without and with the presence of NaCl were quite similar; their maximal values were always just a little higher than the corresponding CMC and with a further growth of the total concentration of benzethonium chloride there was, on the other hand, a marked decrease in the concentration of its free cations in micellar solution.
  • [MeSH-major] Anti-Infective Agents / chemistry. Benzethonium / chemistry. Quaternary Ammonium Compounds / chemistry. Sodium Chloride / chemistry
  • [MeSH-minor] Chemistry, Physical. Micelles. Physicochemical Phenomena. Solutions. Spectrophotometry, Ultraviolet

  • Hazardous Substances Data Bank. BENZETHONIUM CHLORIDE .
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  • (PMID = 16921736.001).
  • [ISSN] 1210-7816
  • [Journal-full-title] Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti
  • [ISO-abbreviation] Ceska Slov Farm
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Micelles; 0 / Quaternary Ammonium Compounds; 0 / Solutions; 1VU15B70BP / Benzethonium; 451W47IQ8X / Sodium Chloride
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37. Sznitowska M, Janicki S, Dabrowska EA, Gajewska M: Physicochemical screening of antimicrobial agents as potential preservatives for submicron emulsions. Eur J Pharm Sci; 2002 Jun;15(5):489-95
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical screening of antimicrobial agents as potential preservatives for submicron emulsions.
  • The emulsions were adjusted to pH 5.0 or 8.2 prior aseptic filtration or thermal sterilization, respectively.
  • The physicochemical stability of the preparations was observed during storage for 2 years at room temperature.
  • Parabens showed the best compatibility but satisfying stability was also observed in emulsions containing phenylethanol, m-cresol and benzalkonium chloride.
  • Only 1.2% of the total content of benzalkonium chloride was found in this phase and incorporation of this compound into different microscopic structures of the emulsion is proposed as a reason for such effect.
  • Preliminary studies on the efficacy of antimicrobial preservation was performed for emulsions containing parabens, benzalkonium chloride or chlorocresol and the negative results bring conclusion that higher concentration of antimicrobials or their combination may be required for efficient preservation of submicron emulsions.
  • [MeSH-major] Anti-Bacterial Agents / chemistry. Preservatives, Pharmaceutical / chemistry
  • [MeSH-minor] Chemistry, Physical. Emulsions. Physicochemical Phenomena. Staphylococcus aureus / drug effects

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  • (PMID = 12036725.001).
  • [ISSN] 0928-0987
  • [Journal-full-title] European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  • [ISO-abbreviation] Eur J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Emulsions; 0 / Preservatives, Pharmaceutical
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38. Jayaraman S, Verkman AS: Quenching mechanism of quinolinium-type chloride-sensitive fluorescent indicators. Biophys Chem; 2000 May 31;85(1):49-57
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quenching mechanism of quinolinium-type chloride-sensitive fluorescent indicators.
  • Quinolinium based Cl- sensitive fluorescent indicators have been used extensively to measure intracellular Cl- activity.
  • Stern-Volmer plots for quenching by Cl-, Br-, SCN-, I-, F-, OAc- and CO3(2-) from both intensity and lifetime measurements were linear.
  • Understanding the mechanism facilitates structure-based predictions of the anion sensitivities of quinolinium indicators to design improved Cl- indicators with tailored properties.
  • [MeSH-major] Chlorides / chemistry. Fluorescent Dyes / chemistry. Quinolinium Compounds / chemistry
  • [MeSH-minor] Chemistry, Physical. Diffusion. Electrochemistry. Isoquinolines / chemistry. Physicochemical Phenomena. Spectrometry, Fluorescence

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  • (PMID = 10885398.001).
  • [ISSN] 0301-4622
  • [Journal-full-title] Biophysical chemistry
  • [ISO-abbreviation] Biophys. Chem.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK35124; United States / NIDDK NIH HHS / DK / DK43840; United States / NHLBI NIH HHS / HL / HL60288
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Chlorides; 0 / Fluorescent Dyes; 0 / Isoquinolines; 0 / Quinolinium Compounds
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39. Tavss EA, Gaffar A, King WJ: Studies on the formation of electrostatic complexes between benzethonium chloride and anionic polymers. J Pharm Sci; 1984 Aug;73(8):1148-52
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Studies on the formation of electrostatic complexes between benzethonium chloride and anionic polymers.
  • The chemistry of a mixture of benzethonium chloride and a copolymer of methoxyethylene-maleic anhydride was investigated.
  • Evidence from dialysis, pH measurements, and stoichiometry demonstrated that the benzethonium cation and the anion of the hydrolyzed copolymer formed an electrostatic complex.
  • The stability of the complex was pH dependent, and it did not form in 50% acetone.
  • The complex was decomposed by simulated saliva, mainly due to calcium and magnesium ions, but was unaffected by salivary proteins.
  • [MeSH-minor] Acetone. Chemistry, Physical. Dialysis. Drug Stability. Humans. Hydrogen-Ion Concentration. Magnesium / analysis. Molecular Weight. Physicochemical Phenomena. Polymers. Saliva / metabolism. Salivary Proteins and Peptides / analysis

  • Hazardous Substances Data Bank. BENZETHONIUM CHLORIDE .
  • Hazardous Substances Data Bank. ACETONE .
  • Hazardous Substances Data Bank. MAGNESIUM, ELEMENTAL .
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  • (PMID = 6548521.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Maleates; 0 / Polyethylenes; 0 / Polymers; 0 / Quaternary Ammonium Compounds; 0 / Salivary Proteins and Peptides; 1364PS73AF / Acetone; 1VU15B70BP / Benzethonium; 9011-16-9 / poly(methyl vinyl ether-co-maleic anhydride); I38ZP9992A / Magnesium
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40. Nakanishi S, Fujii M, Sugamura Y, Suzuki A, Shibata Y, Koizumi N, Watanabe Y: Evaluation of the physicochemical characteristics of crospovidone that influence solid dispersion preparation. Int J Pharm; 2011 Jul 15;413(1-2):119-25
Hazardous Substances Data Bank. POLYVINYLPYRROLIDONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of the physicochemical characteristics of crospovidone that influence solid dispersion preparation.
  • Four types of commercial CroPVP, Polyplasdone XL (XL) used as the initial carrier, Polyplasdone XL10 and INF-10 manufactured by milling XL, and Kollidon CL (CL) marketed by another company, were compared.
  • The limit of the IM-CrosPVP weight ratio with which an SD can be prepared (maximum IM content) was calculated on the basis of the heat of fusion of physical mixtures of IM and CrosPVP with various weight ratios.
  • When CL was used, however, it was about half of that obtained with XL, even though the difference between XL and CL was not observed in the physicochemical characteristics (particle size, specific surface area, flowability, glass transition temperature, IR spectra, and solid state NMR spectra).
  • As determined by pore size distribution measurement, the volume of pore of which size is larger than the particle size of IM was less in CL than in XL.
  • [MeSH-major] Drug Delivery Systems. Pharmaceutic Aids / chemistry. Povidone / chemistry
  • [MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / chemistry. Drug Carriers / chemistry. Drug Compounding. Excipients / chemistry. Hot Temperature. Indomethacin / chemistry. Particle Size. Physicochemical Phenomena. Powders / chemistry. Solubility. Surface Properties. Transition Temperature

  • Hazardous Substances Data Bank. INDOMETHACIN .
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  • [Copyright] Copyright © 2011 Elsevier B.V. All rights reserved.
  • (PMID = 21549186.001).
  • [ISSN] 1873-3476
  • [Journal-full-title] International journal of pharmaceutics
  • [ISO-abbreviation] Int J Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Drug Carriers; 0 / Excipients; 0 / Pharmaceutic Aids; 0 / Powders; 9003-39-8 / Povidone; XXE1CET956 / Indomethacin
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41. Thompson D, Coleman S, Diamond D, Byrne R: Electronic structure calculations and physicochemical experiments quantify the competitive liquid ion association and probe stabilisation effects for nitrobenzospiropyran in phosphonium-based ionic liquids. Phys Chem Chem Phys; 2011 Apr 7;13(13):6156-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Electronic structure calculations and physicochemical experiments quantify the competitive liquid ion association and probe stabilisation effects for nitrobenzospiropyran in phosphonium-based ionic liquids.
  • Liquid ion association in ionic liquids (ILs) has been examined using a comprehensive series of electronic structure calculations that measure the relative extents of ion association and probe stabilisation for the photochromic dye nitrobenzospiropyran (BSP) in a range of ILs featuring both long-tailed phosphonium cations and short-tailed imidazolium cations, paired with both chloride and NTf(2) anions.
  • New physicochemical experiments measured the photochromic properties of BSP in the phosphonium-based room temperature ILs.
  • Taken together, the computed complexation energies and measured spectroscopic properties support recent Walden plots of unusual conductivity-viscosity behaviour obtained for the same ILs and reveal some new features in the atom-scale structure and energetics of local, ion-ion and ion-molecule interactions.
  • Calculations show inter-ion interactions strengthened by between 0.4 and 0.7 eV as stronger constituent ions are used, which contributes to the longer range rigidity of the Cl-based IL structure as reflected in the doubled |zwitterion → closed| probe relaxation time measured for Cl(-)vs. NTf(2)(-) in phosphonium-based ILs.
  • Overall the electronic calculations of local, individual ion-ion and ion-molecule interactions serve to clarify some of the measured physicochemical properties and provide new data for the development of classical force field-based approaches to measure also the longer range effects that, together with the electronic effects, provide the condensed phase IL structure and properties.
  • More generally, the combined simulation and experimental results serve as a further example of how both the polar hydrophilic headgroup and non-polar hydrophobic tail of the constituent ions serve as distinct targets for IL rational design.
  • [MeSH-major] Benzopyrans / chemistry. Electrons. Indoles / chemistry. Ionic Liquids / chemistry. Nitro Compounds / chemistry. Organophosphorus Compounds / chemistry. Quantum Theory
  • [MeSH-minor] Models, Molecular. Physicochemical Phenomena

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  • (PMID = 21350746.001).
  • [ISSN] 1463-9084
  • [Journal-full-title] Physical chemistry chemical physics : PCCP
  • [ISO-abbreviation] Phys Chem Chem Phys
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Benzopyrans; 0 / Indoles; 0 / Ionic Liquids; 0 / Nitro Compounds; 0 / Organophosphorus Compounds; 0 / spiropyran; 0 / tributylmethyl phosphonium chloride
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42. Costa FF, Resende JV, Abreu LR, Goff HD: Effect of calcium chloride addition on ice cream structure and quality. J Dairy Sci; 2008 Jun;91(6):2165-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of calcium chloride addition on ice cream structure and quality.
  • The influence of calcium fortification by the addition of calcium chloride on quality parameters of ice cream based on physical properties was investigated, as was the effect of kappa-carrageenan at modifying the effects of this calcium fortification.
  • Four ice cream mixes of conventional composition, with added kappa-carrageenan (0 or 0.025%) and added calcium chloride (0 or 4.4 g L(-1) = 40 mM of added Ca(2+)), were prepared.
  • Modulated temperature-differential scanning calorimetry was used to investigate the effect of calcium chloride on the nucleation temperature, enthalpy of melting, and freezing point depression.
  • The results demonstrated that the addition of calcium chloride led to a substantial increase in ice crystal sizes and in fat partial coalescence, which were exacerbated by the addition of kappa-carrageenan.
  • These results can be explained by the interaction between Ca(2+) ions and casein micelles, rather than any effects on freezing point depression.
  • The calcium ions led to a more compact micelle, less serum beta-casein, and high fat destabilization, all of which would be expected to reduce macromolecular structure and volume occupancy in the unfrozen phase, which led to increased rates of ice recrystallization.
  • [MeSH-major] Calcium Chloride / pharmacology. Carrageenan / pharmacology. Food Technology. Food, Fortified. Ice Cream / analysis
  • [MeSH-minor] Animals. Calorimetry, Differential Scanning. Cattle. Chemistry, Physical. Crystallization. Dose-Response Relationship, Drug. Fats / analysis. Food Handling / methods. Milk Proteins / analysis. Particle Size. Physicochemical Phenomena. Temperature

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  • (PMID = 18487638.001).
  • [ISSN] 1525-3198
  • [Journal-full-title] Journal of dairy science
  • [ISO-abbreviation] J. Dairy Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fats; 0 / Milk Proteins; 9000-07-1 / Carrageenan; M4I0D6VV5M / Calcium Chloride
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43. Kimura R, Miwa M, Kato Y, Sato M, Yamada S: Relationship between nasal absorption and physicochemical properties of quaternary ammonium compounds. Arch Int Pharmacodyn Ther; 1991 Mar-Apr;310:13-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relationship between nasal absorption and physicochemical properties of quaternary ammonium compounds.
  • The present study was undertaken to investigate the in situ nasal absorption of a series of tetraethylammonium chloride-related aliphatic quaternary ammonium compounds in rats and its relationship with their physicochemical properties (molecular weight and partition coefficient).
  • The nasal absorption rates of ethyltrimethyl-ammonium iodide and tetraethylammonium chloride, with the lowest molecular weight, were the highest, and those of tetra-n-butylammonium chloride and tetra-n-propylammonium bromide, with high molecular weight, were much lower.
  • A physicochemical study has shown that there was a linear relationship between the molecular weight of the ten quaternary ammonium compounds and their partition coefficient, thereby suggesting an increase in lipophilicity with the molecular weight.
  • [MeSH-major] Nasal Mucosa / metabolism. Quaternary Ammonium Compounds / chemistry. Quaternary Ammonium Compounds / pharmacokinetics
  • [MeSH-minor] Absorption. Animals. Chemistry, Physical. Kinetics. Lipids / chemistry. Male. Molecular Weight. Physicochemical Phenomena. Rats. Rats, Inbred Strains. Solubility

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  • (PMID = 1772325.001).
  • [ISSN] 0003-9780
  • [Journal-full-title] Archives internationales de pharmacodynamie et de thérapie
  • [ISO-abbreviation] Arch Int Pharmacodyn Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] BELGIUM
  • [Chemical-registry-number] 0 / Lipids; 0 / Quaternary Ammonium Compounds
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44. Bruckmaier RM, Weiss D, Wiedemann M, Schmitz S, Wendl G: Changes of physicochemical indicators during mastitis and the effects of milk ejection on their sensitivity. J Dairy Res; 2004 Aug;71(3):316-21
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Changes of physicochemical indicators during mastitis and the effects of milk ejection on their sensitivity.
  • We examined the relationship between physicochemical indicators and somatic cells in the milk of dairy cows during experimentally induced mastitis and their significance as indicators for use in controlling udder health.
  • In Expt 1, Escherichia coli lipopolysaccharide (Esch. coli LPS) was injected into the left rear quarter to induce an inflammatory reaction in one quarter in each of six cows.
  • Samples were analysed for SCC, electrical conductivity (EC) and Na+ and Cl- concentrations.
  • During the experimental inflammation SCC, EC, Na+ and Cl- peaked at 12 h from LPS administration and values in treated quarters (T) at this time were elevated to 7900, 157, 501 and 169% of the values in untreated quarters, respectively.
  • In Expt 2, SCC, EC, Na+ and Cl- in high SCC quarters were 2520, 121, 283 and 141% of low SCC quarters at the start of stimulation (t=0 s), respectively.
  • Highly significant (P<0.001) differences in EC, Na+ and Cl- between high and low SCC quarters disappeared owing to the onset of alveolar milk ejection 100 s after the first contact with the teat.
  • EC, Na+ or Cl- were useful tools only if the measurements were performed in cisternal milk before the start of alveolar milk ejection.
  • [MeSH-minor] Animals. Biomarkers. Cell Count. Chemistry, Physical. Chlorides / analysis. Electric Conductivity. Escherichia coli. Female. Kinetics. Lipopolysaccharides / administration & dosage. Milk / cytology. Physicochemical Phenomena. Sensitivity and Specificity. Sodium / analysis

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  • (PMID = 15354578.001).
  • [ISSN] 0022-0299
  • [Journal-full-title] The Journal of dairy research
  • [ISO-abbreviation] J. Dairy Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Chlorides; 0 / Lipopolysaccharides; 9NEZ333N27 / Sodium
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45. Zatloukal Z: [Effect of pilocarpine chloride on pseudoplastic hydrogel]. Ceska Slov Farm; 2003 May;52(3):131-5
Hazardous Substances Data Bank. PILOCARPINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect of pilocarpine chloride on pseudoplastic hydrogel].
  • The obtained equations make it possible not only to estimate apparent and real viscosity, but also the area under the curve of the pseudoplastic rheogram.
  • At a temperature of 32 degrees C, analysis of variance demonstrated a significant diminution of this area in the presence of about 2% of pilocarpinium chloride.
  • [MeSH-major] Hydrogel / chemistry. Methylcellulose / analogs & derivatives. Methylcellulose / chemistry. Pilocarpine
  • [MeSH-minor] Chemistry, Physical. Elasticity. Hypromellose Derivatives. Physicochemical Phenomena. Viscosity

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  • (PMID = 12789773.001).
  • [ISSN] 1210-7816
  • [Journal-full-title] Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti
  • [ISO-abbreviation] Ceska Slov Farm
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 01MI4Q9DI3 / Pilocarpine; 25852-47-5 / Hydrogel; 3NXW29V3WO / Hypromellose Derivatives; 9004-67-5 / Methylcellulose
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46. Wu CD, Liu XH, Fan JC, Wang LS: Ultrasonic destruction of chloroform and carbon tetrachloride in aqueous solution. J Environ Sci Health A Tox Hazard Subst Environ Eng; 2001;36(6):947-55
Hazardous Substances Data Bank. CHLOROFORM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The influences of initial concentration, bicarbonate/chloride, and acoustical intensity on the destruction rates have been observed.
  • However, their destruction rates increased with increasing acoustical intensity and were independent of addition of bicarbonate or chloride.
  • The resulting yield of ionic product (Cl-) for chloroform was determined.
  • [MeSH-major] Carbon Tetrachloride / chemistry. Chloroform / chemistry. Solvents / chemistry. Ultrasonics. Water Pollutants, Chemical / analysis
  • [MeSH-minor] Chemistry, Physical. Kinetics. Physicochemical Phenomena. Water Pollution / prevention & control

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  • (PMID = 11501317.001).
  • [ISSN] 1093-4529
  • [Journal-full-title] Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
  • [ISO-abbreviation] J Environ Sci Health A Tox Hazard Subst Environ Eng
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Solvents; 0 / Water Pollutants, Chemical; 7V31YC746X / Chloroform; CL2T97X0V0 / Carbon Tetrachloride
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47. Matsuda Y, Kawaguchi S, Kobayashi H, Nishijo J: Physicochemical characterization of spray-dried phenylbutazone polymorphs. J Pharm Sci; 1984 Feb;73(2):173-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical characterization of spray-dried phenylbutazone polymorphs.
  • Three different crystalline forms (delta, beta, and epsilon) could be prepared from methylene chloride solution by varying the drying temperature of sprayed droplets from 120 degrees C to 30 degrees C.
  • Form epsilon, the fifth polymorph of phenylbutazone, was confirmed as a novel crystalline form which could not be prepared by recrystallization techniques.
  • [MeSH-minor] Calorimetry / methods. Chemistry, Physical. Crystallization. Microscopy, Electron, Scanning. Physicochemical Phenomena. Solubility. Spectrophotometry, Infrared. Thermodynamics. X-Ray Diffraction

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  • (PMID = 6707878.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] GN5P7K3T8S / Phenylbutazone
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48. Do Duc H, Tissot P, Meyer JM: Potential sweep and intensiostatic pulse studies of Sn, Sn8Hg and dental amalgam in chloride solution. J Dent Res; 1979 Feb;58(2):576-83
Hazardous Substances Data Bank. TIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Potential sweep and intensiostatic pulse studies of Sn, Sn8Hg and dental amalgam in chloride solution.
  • The anodic behavior of the Sn, the Sn8Hg (gamma2) phase and the dental amalgam in a chloride solution has been investigated by means of the linear potential sweep and of the intensiostatic pulse method.
  • The results indicate that anodic current varies with chloride concentration and that dissolution occurs prior to passivation of the electrode.
  • [MeSH-minor] Chemical Phenomena. Chemistry, Physical. Corrosion. Electrochemistry. Oxidation-Reduction. Oxides. Silver

  • MedlinePlus Health Information. consumer health - Mercury.
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  • (PMID = 283086.001).
  • [ISSN] 0022-0345
  • [Journal-full-title] Journal of dental research
  • [ISO-abbreviation] J. Dent. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chlorides; 0 / Oxides; 3M4G523W1G / Silver; 7440-31-5 / Tin; 8049-85-2 / Dental Amalgam; FXS1BY2PGL / Mercury
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49. Li XH, Lah MS, Pecoraro VL: Structural characterization of the manganese(IV) Schiff-base complex MnIV(5-Cl-SALAHP)2. Acta Crystallogr C; 1989 Oct 15;45 ( Pt 10):1517-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Structural characterization of the manganese(IV) Schiff-base complex MnIV(5-Cl-SALAHP)2.
  • The title complex MnIV(5-Cl-SALAHP)2 [5-Cl-SALAHP = 3-(5-chlorosalicylideneamino)propanolato] displays a regular octahedral geometry.
  • The 5-Cl-SALAHP ligand is tridentate, forming a meridional chelate with one phenolato oxygen (Mn-Oavg = 1.90 A), one alkoxide oxygen (Mn-Oavg = 1.85 A) and one imine nitrogen (Mn-Navg = 2.02 A) coordinated to the metal.
  • Previous studies have shown that MnIV(5-Cl-SALAHP)2 displays a rhombic EPR spectrum with well-resolved 55Mn hyperfine structure on gx, gy and gz.
  • [MeSH-minor] Chemistry, Physical. Molecular Conformation. Physicochemical Phenomena. Schiff Bases. Temperature. X-Ray Diffraction

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  • (PMID = 2610956.001).
  • [ISSN] 0108-2701
  • [Journal-full-title] Acta crystallographica. Section C, Crystal structure communications
  • [ISO-abbreviation] Acta Crystallogr C
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM39406
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] DENMARK
  • [Chemical-registry-number] 0 / Organometallic Compounds; 0 / Schiff Bases; 124430-02-0 / bis(3-(5-chlorosalicylideneamino)propanolato-O,N-O')manganese(IV)
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50. Jones DS, McGovern JG, Woolfson AD, Adair CG, Gorman SP: Physicochemical characterization of hexetidine-impregnated endotracheal tube poly(vinyl chloride) and resistance to adherence of respiratory bacterial pathogens. Pharm Res; 2002 Jun;19(6):818-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical characterization of hexetidine-impregnated endotracheal tube poly(vinyl chloride) and resistance to adherence of respiratory bacterial pathogens.
  • This study describes the physicochemical properties of hexetidine-impregnated poly(vinyl chloride) (PVC) endotracheal tube (ET) biomaterials and their resistance to microbial adherence (Staphylococcus aureus and Pseudomonas aeruginosa).
  • Increasing the concentration of hexetidine from 1% to 10% (w/w) (but not from 10% to 20% w/w) increased the subsequent rate of drug release.
  • CONCLUSIONS: ET PVC containing 1% (w/w) hexetidine offered an appropriate balance between suitable physicochemical properties and resistance to microbial adherence.
  • [MeSH-major] Bacterial Adhesion. Hexetidine / pharmacokinetics. Intubation, Intratracheal. Polyvinyl Chloride / pharmacokinetics. Pseudomonas aeruginosa / drug effects. Staphylococcus aureus / drug effects
  • [MeSH-minor] Analysis of Variance. Biofilms / drug effects. Biofilms / growth & development. Chemistry, Physical. Drug Resistance / physiology. Humans. Physicochemical Phenomena. Pneumonia, Bacterial / prevention & control. Respiratory Tract Infections / prevention & control

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  • (PMID = 12134952.001).
  • [ISSN] 0724-8741
  • [Journal-full-title] Pharmaceutical research
  • [ISO-abbreviation] Pharm. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 852A84Y8LS / Hexetidine; 9002-86-2 / Polyvinyl Chloride
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51. Naumov P, Anastasova F: Experimental and theoretical vibrational study of isatin, its 5-(NO2, F, Cl, Br, I, CH3) analogues and the isatinato anion. Spectrochim Acta A Mol Biomol Spectrosc; 2001 Mar 1;57(3):469-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Experimental and theoretical vibrational study of isatin, its 5-(NO2, F, Cl, Br, I, CH3) analogues and the isatinato anion.
  • Effects of 5-R substitution (R = NO2, F, Cl, Br, I, CH3) and N-deprotonation on the 4000-400 cm(-1) region of the low temperature FT IR spectrum and the molecular structure of solid isatin are investigated.
  • Theoretical v(CO) frequency of isatin is lowered for about 180 cm(-1) upon conversion into isatinato ion.
  • [MeSH-major] Halogens / chemistry. Isatin / analogs & derivatives. Isatin / chemistry
  • [MeSH-minor] Chemistry, Physical. Molecular Structure. Physicochemical Phenomena. Spectroscopy, Fourier Transform Infrared

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  • (PMID = 11300558.001).
  • [ISSN] 1386-1425
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Halogens; 82X95S7M06 / Isatin
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52. Yu R, Koran A 3rd, Powers JM: Effect of processing temperature on the properties of a polyvinyl chloride maxillofacial elastomer. J Dent Res; 1983 Oct;62(10):1098-100
Hazardous Substances Data Bank. POLYVINYL CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of processing temperature on the properties of a polyvinyl chloride maxillofacial elastomer.
  • Mechanical properties and color of a plasticized polyvinyl chloride (PVC) maxillofacial elastomer were evaluated at processing temperatures from 140 to 190 degrees C.
  • [MeSH-major] Maxillofacial Prosthesis. Polyvinyl Chloride. Polyvinyls. Temperature
  • [MeSH-minor] Chemical Phenomena. Chemistry, Physical. Color. Elasticity. Hardness. Tensile Strength

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  • (PMID = 6578242.001).
  • [ISSN] 0022-0345
  • [Journal-full-title] Journal of dental research
  • [ISO-abbreviation] J. Dent. Res.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / DE-04136
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Polyvinyls; 9002-86-2 / Polyvinyl Chloride
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53. Yoshimoto M, Tanimura K, Tokunaga K, Kamimura A: Hydrolysis of insoluble cellulose to glucose catalyzed by cellulase-containing liposomes in an aqueous solution of 1-butyl-3-methylimidazolium chloride. Biotechnol Prog; 2013 Sep-Oct;29(5):1190-6
Hazardous Substances Data Bank. GLUCOSE .

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  • [Title] Hydrolysis of insoluble cellulose to glucose catalyzed by cellulase-containing liposomes in an aqueous solution of 1-butyl-3-methylimidazolium chloride.
  • The liposomal cellulase and free enzyme were examined in their hydrolytic activities to insoluble cellulose powder CC31 in the acetate buffer solution (pH 4.8) of 15 w/w% [Bmim][Cl] (1-butyl-3-methylimidazolium chloride).
  • The free cellulase was deactivated more rapidly than the liposomal cellulase in catalyzing the hydrolysis of 2.0 g/l CC31 at 45°C in the presence of [Bmim][Cl] for 48 h.
  • The activities of liposomal and free cellulase to cellobiose as soluble substrate were less susceptible to [Bmim][Cl] than their cellulolytic activities to CC31, meaning that β-glucosidase is relatively stable among the three enzyme components of cellulase.
  • The rate of glucose production could be appreciably improved by the pretreatment of CC31 with [Bmim][Cl] alone at 120°C for 30 min followed by the liposomal cellulase-catalyzed hydrolysis of the substrate at 45°C at the [Bmim][Cl] concentration of 15 w/w%.
  • [MeSH-major] Cellulase / metabolism. Cellulose / chemistry. Glucose / chemistry. Imidazoles / chemistry. Liposomes / chemistry
  • [MeSH-minor] Cellobiose / metabolism. Hydrolysis. Industrial Microbiology. Physicochemical Phenomena. Trichoderma / enzymology. beta-Glucosidase / metabolism

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  • [Copyright] © 2013 American Institute of Chemical Engineers.
  • (PMID = 23813807.001).
  • [ISSN] 1520-6033
  • [Journal-full-title] Biotechnology progress
  • [ISO-abbreviation] Biotechnol. Prog.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 1-butyl-3-methylimidazolium chloride; 0 / Imidazoles; 0 / Liposomes; 16462-44-5 / Cellobiose; 9004-34-6 / Cellulose; EC 3.2.1.21 / beta-Glucosidase; EC 3.2.1.4 / Cellulase; IY9XDZ35W2 / Glucose
  • [Keywords] NOTNLM ; cellulase / hydrolysis / insoluble cellulose / ionic liquid / liposomes
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54. Nath K, Panchani S, Bhakhar MS, Chatrola S: Preparation of activated carbon from dried pods of Prosopis cineraria with zinc chloride activation for the removal of phenol. Environ Sci Pollut Res Int; 2013 Jun;20(6):4030-45
Hazardous Substances Data Bank. ZINC CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preparation of activated carbon from dried pods of Prosopis cineraria with zinc chloride activation for the removal of phenol.
  • In the present work, dried pods of Prosopis cineraria-a novel and low-cost agrowaste material-were used to prepare activated carbons by zinc chloride activation.
  • Batch adsorption experiments were carried out to study the effects of various physicochemical parameters such as initial phenol concentration, adsorbent dose, initial solution pH, and temperature.
  • The favorable pH for maximum phenol adsorption was 4.0.
  • [MeSH-major] Carbon / chemistry. Chlorides / chemistry. Phenol / isolation & purification. Prosopis / chemistry. Zinc Compounds / chemistry
  • [MeSH-minor] Adsorption. Diffusion. Hydrogen-Ion Concentration. Kinetics. Physicochemical Phenomena. Solutions. Temperature. Thermodynamics. Waste Water / analysis

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  • (PMID = 23212266.001).
  • [ISSN] 1614-7499
  • [Journal-full-title] Environmental science and pollution research international
  • [ISO-abbreviation] Environ Sci Pollut Res Int
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Chlorides; 0 / Solutions; 0 / Waste Water; 0 / Zinc Compounds; 339NCG44TV / Phenol; 7440-44-0 / Carbon; 86Q357L16B / zinc chloride
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55. Jiang Z, Lv L, Zhang W, Du Q, Pan B, Yang L, Zhang Q: Nitrate reduction using nanosized zero-valent iron supported by polystyrene resins: role of surface functional groups. Water Res; 2011 Mar;45(6):2191-8
Hazardous Substances Data Bank. IRON, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To probe the role of host chemistry in formation and properties of the inside nano-zero valent iron (nZVI), we encapsulated nZVI within porous polystyrene resins functionalized with -CH(2)Cl and -CH(2)N(+)(CH(3))(3) respectively and obtained two hybrid nZVIs denoted Cl-S-ZVI and N-S-ZVI.
  • 14.5% (in Fe mass) of nZVI particles were distributed in N-S within a ring-like region (about 0.10 mm in thickness) of size around ∼ 5 nm, whereas only 4.0% of nZVI particles were entrapped near the outer surface of Cl-S of size > 20 nm.
  • -CH(2)N(+)(CH(3))(3) is more favorable than -CH(2)Cl to inhibit nZVI dissolution into Fe(2+) ions under acidic pH (3.0-5.5).
  • 97.2% of nitrate was converted into ammonium when introducing 0.12 g N-S-ZVI into 50 mL 50 mg N/L nitrate solution, while that for Cl-S-ZVI was 79.8% under identical Fe/N molar ratio.
  • Under pH = 2 of the effectiveness of nZVI was 88.8% for nitrate reduction, whereas that for Cl-S-ZVI was only 14.6% under similar conditions.
  • Nitrate reduction by N-S-ZVI exhibits relatively slower kinetics than Cl-S-ZVI, which may be related to different nZVI distribution of both composites.
  • The coexisting chloride and sulfate co-ions are favorable for the reactivity enhancement of N-S-ZVI whereas slightly unfavorable for Cl-S-ZVI.
  • The results demonstrated that support chemistry plays a significant role in formation and reactivity of the encapsulated nZVI, and may shed new light on design and fabrication of hybrid nZVIs for environmental remediation.
  • [MeSH-major] Iron / chemistry. Nanoparticles / chemistry. Nitrates / chemistry. Particle Size. Polystyrenes / chemistry. Resins, Synthetic / chemistry
  • [MeSH-minor] Hydrogen-Ion Concentration. Kinetics. Oxidation-Reduction. Physicochemical Phenomena. Solutions. Surface Properties. X-Ray Diffraction

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  • [Copyright] Copyright © 2011 Elsevier Ltd. All rights reserved.
  • (PMID = 21316071.001).
  • [ISSN] 1879-2448
  • [Journal-full-title] Water research
  • [ISO-abbreviation] Water Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Nitrates; 0 / Polystyrenes; 0 / Resins, Synthetic; 0 / Solutions; E1UOL152H7 / Iron
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56. Yoo SH, Lee KH, Lee JS, Cha J, Park CS, Lee HG: Physicochemical properties and biological activities of DEAE-derivatized Sphingomonas gellan. J Agric Food Chem; 2005 Aug 10;53(16):6235-9
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical properties and biological activities of DEAE-derivatized Sphingomonas gellan.
  • Physicochemical characteristics and biological activities of Sphingomonas gellan (S-gellan) were investigated.
  • The S-gellan was chemically derivatized with diethylaminoethyl chloride-HCl (DEAE-HCl), and the resulting modified S-gellan contained both positive and negative charges.
  • Up to 9 h of dialysis, the derivatized S-gellan released 29.3% less of cholic acid compared to the control group that did not contain S-gellan.
  • [MeSH-major] Ethanolamines / chemistry. Polysaccharides, Bacterial / chemistry. Sphingomonas / chemistry
  • [MeSH-minor] Bile Acids and Salts / metabolism. Carbohydrates / analysis. Chemistry, Physical. Magnetic Resonance Spectroscopy. Physicochemical Phenomena. Solubility. Spectrophotometry, Infrared

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  • (PMID = 16076099.001).
  • [ISSN] 0021-8561
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bile Acids and Salts; 0 / Carbohydrates; 0 / Ethanolamines; 0 / Polysaccharides, Bacterial; 71010-52-1 / gellan gum; S6DL4M053U / 2-diethylaminoethanol
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57. Han J, Koutmos M, Ahmad SA, Coucouvanis D: Rational synthesis of high nuclearity Mo/Fe/S clusters: the reductive coupling approach in the convenient synthesis of (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et, (n)Pr, (n)Bu] and the new [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl]-1/2(Fe(PEt(3))(2)(MeCN)(4)) and (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) clusters. Inorg Chem; 2001 Nov 5;40(23):5985-99
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rational synthesis of high nuclearity Mo/Fe/S clusters: the reductive coupling approach in the convenient synthesis of (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et, (n)Pr, (n)Bu] and the new [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl]-1/2(Fe(PEt(3))(2)(MeCN)(4)) and (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) clusters.
  • A general method for the synthesis of high nuclearity Mo/Fe/S clusters is presented and involves the reductive coupling of the (Et(4)N)(2)[(Cl(4)-cat)MoOFeS(2)Cl(2)] (I) and (Et(4)N)(2)[Fe(2)S(2)Cl(4)] (II) clusters.
  • The reaction of I and II with Fe(PR(3))(2)Cl(2) or sodium salts of noncoordinating anions such as NaPF(6) or NaBPh(4) in the presence of PR(3) (R = Et, (n)Pr, or (n)Bu) affords (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et (IIIa), (n)Pr (IIIb), (n)Bu (IIIc)], Fe(6)S(6)(PEt(3))(4)Cl(2) (IV) and (PF(6))[Fe(6)S(8)(P(n)Pr(3))(6)] (V) as byproducts.
  • The isolation of (Et(4)N)[Fe(PEt(3))Cl(3)] (VI), NaCl, and SPEt(3) supports a reductive coupling mechanism.
  • The reductive coupling reaction between I and II by PEt(3) and NaPF(6) in a 1:1 ratio produces the (Et(4)N)(2)[(Cl(4)-cat)Mo(L)Fe(3)S(4)Cl(3)] clusters [L = MeCN (VIIa), THF (VIIb)].
  • The hitherto unknown [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl](+) cluster (VIII) has been isolated as the 2:1 salt of the (Fe(PEt(3))(2)(MeCN)(4))(2+) cation after the reductive self-coupling reaction of I in the presence of Fe(PEt(3))(2)Cl(2).
  • The reductive coupling of compound I also affords in low yield the new (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) cluster (X) as a byproduct.
  • [MeSH-major] Chemistry, Organic / methods. Organometallic Compounds
  • [MeSH-minor] Chemistry, Physical. Chlorides / chemistry. Crystallography, X-Ray. Iron / chemistry. Molecular Conformation. Molecular Structure. Molybdenum / chemistry. Physicochemical Phenomena. Spectrophotometry, Ultraviolet. Spectroscopy, Fourier Transform Infrared. Spectrum Analysis. Sulfur / chemistry

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  • (PMID = 11681915.001).
  • [ISSN] 0020-1669
  • [Journal-full-title] Inorganic chemistry
  • [ISO-abbreviation] Inorg Chem
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM33080
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chlorides; 0 / Organometallic Compounds; 70FD1KFU70 / Sulfur; 81AH48963U / Molybdenum; E1UOL152H7 / Iron
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58. Almaas R, Robertson B, Linderholm B, Lundberg E, Saugstad OD, Moen A: Reversal of meconium inhibition of pulmonary surfactant by ferric chloride, copper chloride, and acetic acid. Am J Respir Crit Care Med; 2000 Nov;162(5):1789-94
Hazardous Substances Data Bank. FERRIC CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reversal of meconium inhibition of pulmonary surfactant by ferric chloride, copper chloride, and acetic acid.
  • Ferric chloride and copper chloride completely reversed the inhibitory effect of meconium.
  • Meconium also prevented effective spreading of surfactant in a Wilhelmy balance system, and this inhibitory effect was counteracted by addition of ferric chloride.
  • Ferric chloride restored the number of microbubbles.
  • Addition of ferric chloride or copper chloride to surfactant/meconium lowers pH, and pH adjustment by acetic acid also reversed the inhibitory effect of meconium.
  • Together with the fact that the iron-chelator deferoxamine did not attenuate the effect of ferric chloride this suggests that the observed contrainhibition is caused by lowering of pH, and that meconium inhibition of surfactant is pH-dependent.
  • Lowering pH from 6.2 to 5-5.5 abolished the inhibitory effects of meconium on surfactant.
  • Inhibition of 2.5 mg/ml of Curosurf with plasma could also be reversed by increasing amounts of ferric chloride.
  • We conclude that the inhibitory effect of meconium on surfactant in vitro can be abolished by addition of ferric chloride, copper chloride, or acetic acid.
  • [MeSH-minor] Chemistry, Physical. Chlorides. Dose-Response Relationship, Drug. Humans. Hydrogen-Ion Concentration. In Vitro Techniques. Infant, Newborn. Lipids / antagonists & inhibitors. Lipids / chemistry. Microspheres. Physicochemical Phenomena

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  • (PMID = 11069814.001).
  • [ISSN] 1073-449X
  • [Journal-full-title] American journal of respiratory and critical care medicine
  • [ISO-abbreviation] Am. J. Respir. Crit. Care Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Biological Products; 0 / Chlorides; 0 / Ferric Compounds; 0 / Lipids; 0 / Organometallic Compounds; 0 / Phospholipids; 0 / Pulmonary Surfactants; 0 / SF-RI 1, bovine surfactant preparation; 108778-82-1 / beractant; KE3U2023NP / poractant alfa; Q40Q9N063P / Acetic Acid; U38V3ZVV3V / ferric chloride
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59. Yeeprae W, Kawakami S, Suzuki S, Yamashita F, Hashida M: Physicochemical and pharmacokinetic characteristics of cationic liposomes. Pharmazie; 2006 Feb;61(2):102-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical and pharmacokinetic characteristics of cationic liposomes.
  • After intravenous administration of plasmid DNA (pDNA)/cationic liposome complexes, the gene expression is predominantly observed in the lung due to the physicochemical properties of the liposome complexes and the physiology of the lung.
  • To determine the physicochemical properties and distribution behavior of cationic liposomes for lung-selective drug and/or gene delivery systems, N-[1-(2,3-dioleyloxy)propyl]-n,n,n-trimethylammonium chloride (DOTMA)/cholesterol and 1,2-dioleoyl-3-trimethyl-ammoniopropane (DOTAP)/cholesterol liposomes were studied.
  • The distribution characteristics of DOTMA/cholesterol and DOTAP/cholesterol liposomes were almost identical due to the similarities in their physicochemical properties.
  • [MeSH-major] Drug Carriers / chemistry. Drug Carriers / pharmacokinetics. Liposomes / chemistry. Liposomes / pharmacokinetics
  • [MeSH-minor] Animals. Area Under Curve. Chemistry, Physical. Cholesterol / chemistry. Drug Delivery Systems. Electrochemistry. Fatty Acids, Monounsaturated. Female. Mice. Mice, Inbred ICR. Particle Size. Physicochemical Phenomena. Quaternary Ammonium Compounds

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  • (PMID = 16526555.001).
  • [ISSN] 0031-7144
  • [Journal-full-title] Die Pharmazie
  • [ISO-abbreviation] Pharmazie
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Drug Carriers; 0 / Fatty Acids, Monounsaturated; 0 / Liposomes; 0 / Quaternary Ammonium Compounds; 104162-48-3 / N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium; 113669-21-9 / 1,2-dioleoyloxy-3-(trimethylammonium)propane; 97C5T2UQ7J / Cholesterol
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60. Lopez JL, García Einschlag FS, Rives CV, Villata LS, Capparelli AL: Physicochemical and toxicological studies on 4-chloro-3,5-dinitrobenzoic acid in aqueous solutions. Environ Toxicol Chem; 2004 May;23(5):1129-35
Hazardous Substances Data Bank. CHLORINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical and toxicological studies on 4-chloro-3,5-dinitrobenzoic acid in aqueous solutions.
  • Physicochemical characterization of hazardous compounds often is required for the development of structure-reactivity correlations.
  • Physical, chemical, and toxicological properties of target pollutants require determination for an efficient application of wastewater treatments.
  • In the present work, we chose a chloro-nitro-aromatic derivative (4-chloro-3,5-dinitrobenzoic acid [CDNBA]), as a model compound on which to perform physicochemical and toxicological studies.
  • Several properties of CDNBA are not available in the literature, although many aromatic nitro-compounds are considered hazardous materials.
  • Measurements of solubility in water, acid dissociation constant, and kinetic parameters for the nucleophilic substitution of chlorine atom in alkaline media are reported.
  • The bimolecular rate constant for the reaction of CDNB- and hydroxyl ion (HO) measured at room temperature and 0.1 M of ionic strength was 5.92/M x s, and the activation energy for this process was 70.7 +/- 3.4 kJ/mol.
  • Cytotoxicity assays with aqueous suspensions of Tetrahymena pyriformis showed lethal effects due to the pH change induced by CDNBA.

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  • (PMID = 15180363.001).
  • [ISSN] 0730-7268
  • [Journal-full-title] Environmental toxicology and chemistry
  • [ISO-abbreviation] Environ. Toxicol. Chem.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acids; 0 / Buffers; 0 / Chlorobenzoates; 0 / Hydroxides; 0 / Solutions; 059QF0KO0R / Water; 118-97-8 / 4-chloro-3,5-dinitrobenzoate; 4R7X1O2820 / Chlorine; 9159UV381P / hydroxide ion
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61. Palaghias G: Corrosion of dental amalgams in solutions of sodium chloride, sodium sulfide and ammonia. Scand J Dent Res; 1986 Jun;94(3):274-80
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  • [Title] Corrosion of dental amalgams in solutions of sodium chloride, sodium sulfide and ammonia.
  • Specimens were prepared from three different dental amalgams and were immersed in 0.5% aqueous solutions of sodium sulfide, ammonia and sodium chloride.
  • Zinc was the first element to be released in sodium chloride solutions.
  • [MeSH-major] Ammonia. Dental Amalgam. Sodium Chloride. Sulfides
  • [MeSH-minor] Chemistry, Physical. Copper / analysis. Corrosion. Hydrogen-Ion Concentration. Mercury / analysis. Physicochemical Phenomena. Solutions. Surface Properties. Time Factors. Zinc / analysis

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  • (PMID = 3461549.001).
  • [ISSN] 0029-845X
  • [Journal-full-title] Scandinavian journal of dental research
  • [ISO-abbreviation] Scand J Dent Res
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] DENMARK
  • [Chemical-registry-number] 0 / Solutions; 0 / Sulfides; 451W47IQ8X / Sodium Chloride; 7664-41-7 / Ammonia; 789U1901C5 / Copper; 8049-85-2 / Dental Amalgam; C02T02993U / sodium sulfide; FXS1BY2PGL / Mercury; J41CSQ7QDS / Zinc
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62. Muñoz-Úbeda M, Misra SK, Barrán-Berdón AL, Datta S, Aicart-Ramos C, Castro-Hartmann P, Kondaiah P, Junquera E, Bhattacharya S, Aicart E: How does the spacer length of cationic gemini lipids influence the lipoplex formation with plasmid DNA? Physicochemical and biochemical characterizations and their relevance in gene therapy. Biomacromolecules; 2012 Dec 10;13(12):3926-37
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] How does the spacer length of cationic gemini lipids influence the lipoplex formation with plasmid DNA? Physicochemical and biochemical characterizations and their relevance in gene therapy.
  • Lipoplexes formed by the pEGFP-C3 plasmid DNA (pDNA) and lipid mixtures containing cationic gemini surfactant of the 1,2-bis(hexadecyl dimethyl ammonium) alkanes family referred to as C16CnC16, where n=2, 3, 5, or 12, and the zwitterionic helper lipid, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) have been studied from a wide variety of physical, chemical, and biological standpoints.
  • 2011, 133, 18014), the detailed physicochemical and biological studies confirm that, in the presence of the studied series lipid mixtures, plasmid DNA is compacted with a large number of its associated Na+ counterions.
  • Consequently, the cationic lipid (CL) complexes prepared with pDNA and CL/DOPE mixtures to be used in gene transfection require significantly less amount of CL than the one estimated assuming a value of qDNA−=−2.
  • Depending on the CL molar composition, α, of the lipid mixture, and the effective charge ratio of the lipoplex, ρeff, the reported SAXS data indicate the presence of two or three structures in the same lipoplex, one in the DOPE-rich region, other in the CL-rich region, and another one present at any CL composition.
  • Each lipid combination was safe and did not show any significant levels of toxicity.
  • [MeSH-major] Cations / chemistry. DNA / chemistry. Lipids / chemistry. Physicochemical Phenomena. Plasmids / chemistry
  • [MeSH-minor] Animals. CHO Cells. Cell Survival. Cricetinae. Electrophoresis, Agar Gel. Genetic Therapy. Green Fluorescent Proteins / genetics. Green Fluorescent Proteins / metabolism. HEK293 Cells. HeLa Cells. Humans. Liposomes / chemistry. Microscopy, Confocal. Phosphatidylethanolamines / chemistry. Scattering, Small Angle. Surface-Active Agents / chemistry. Transfection. Viscosity. X-Ray Diffraction / methods

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  • (PMID = 23130552.001).
  • [ISSN] 1526-4602
  • [Journal-full-title] Biomacromolecules
  • [ISO-abbreviation] Biomacromolecules
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cations; 0 / Lipids; 0 / Liposomes; 0 / Phosphatidylethanolamines; 0 / Surface-Active Agents; 147336-22-9 / Green Fluorescent Proteins; 2462-63-7 / dioleoyl phosphatidylethanolamine; 9007-49-2 / DNA
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63. Sarkisian BG, Novokhatskiĭ AS, Berezina LK, L'vov DK: [Physicochemical properties of the Okhotsky virus]. Vopr Virusol; 1979 Jul-Aug;(4):373-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Physicochemical properties of the Okhotsky virus].
  • [Transliterated title] Nekotorye fiziko-khimicheskie svoĭstva virusa Okhotskiĭ.
  • The buoyant densities of its virions were determined in sucrose and cesium chloride gradients and found to be 1.16--1.18 and 1.36 g/cm3, respectively.
  • The study of the above physico-chemical properties confirmed the appurtenance of Okhotsky virus to the genus Orbivirus of the Reoviridae family.
  • [MeSH-minor] Animals. Centrifugation, Density Gradient. Chemistry, Physical. Genes, Viral. Mice. Physicochemical Phenomena. RNA, Viral / analysis. RNA, Viral / isolation & purification. Virus Cultivation / methods

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  • (PMID = 225884.001).
  • [ISSN] 0507-4088
  • [Journal-full-title] Voprosy virusologii
  • [ISO-abbreviation] Vopr. Virusol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] 0 / RNA, Viral
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64. Meissner T, Eisenbeiss F, Jastorff B: New leading electrolyte for the direct determination of chloride and other anions in analytical isotachophoresis. J Chromatogr A; 1999 Apr 9;838(1-2):81-8
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  • [Title] New leading electrolyte for the direct determination of chloride and other anions in analytical isotachophoresis.
  • In a number of experiments it was shown that the dithionate ion possesses a higher effective mobility than the chloride ion in aqueous solution, thus enabling the direct and simultaneous isotachophoretic determination of chloride and other anions.
  • Based on this pKa value, theoretical calculations and the experimentally observed effective mobility of the dithionate ion indicate a higher effective mobility compared to the chloride ion from pH 3.
  • Taking into account the physico-chemical properties of the dithionate, its unrestricted use as isotachophoretic leading ion was confirmed.
  • Based on the dithionate ion, new electrolyte systems for the determination of chloride were used.
  • One system was optimised for the determination of chloride and other low-molecular-mass anions and applied to the analysis of waste water and drinking water.
  • The water samples were analysed in parallel by ion chromatography and compared with the isotachophoretic results.
  • [MeSH-minor] Calcium. Chemistry, Physical. Drug Stability. Hydrogen-Ion Concentration. Indicators and Reagents. Magnesium. Molecular Weight. Physicochemical Phenomena. Solutions. Water / chemistry

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  • (PMID = 10327633.001).
  • [ISSN] 0021-9673
  • [Journal-full-title] Journal of chromatography. A
  • [ISO-abbreviation] J Chromatogr A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Anions; 0 / Chlorides; 0 / Indicators and Reagents; 0 / Solutions; 0 / Sulfates; 059QF0KO0R / Water; I38ZP9992A / Magnesium; RPF7Z41GAW / sodium dithionate; SY7Q814VUP / Calcium
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65. Scouten WH, van den Tweel W, Delhaes D, Kranenberg H, Dekker M: Sulfonyl chloride activation of hydroxylic materials. J Chromatogr; 1986 Apr 11;376:289-98
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  • [Title] Sulfonyl chloride activation of hydroxylic materials.
  • The primary basis for development of such reagents has been pentafluorobenzenesulfonyl chloride and tresyl chloride, both of which are excellent activating agents.
  • [MeSH-minor] Chemistry, Physical. Chromatography, Affinity. Hydrogen-Ion Concentration. Ligands. Physicochemical Phenomena

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  • (PMID = 3711196.001).
  • [Journal-full-title] Journal of chromatography
  • [ISO-abbreviation] J. Chromatogr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Ligands; 0 / Sulfinic Acids; 7791-25-5 / sulfonyl chloride
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66. Kuroda R, Shinomiya M: Structures of new DNA photocleaving agents: 3,6-bis(dimethylamino)-10- [6-(4-nitrobenzoyloxy)hexyl]acridinium chloride (I) and 9-([6-(4- nitrobenzoyloxy)-hexyl]amino)acridinium chloride monohydrate (II). Acta Crystallogr C; 1992 Mar 15;48 ( Pt 3):512-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Structures of new DNA photocleaving agents: 3,6-bis(dimethylamino)-10- [6-(4-nitrobenzoyloxy)hexyl]acridinium chloride (I) and 9-([6-(4- nitrobenzoyloxy)-hexyl]amino)acridinium chloride monohydrate (II).
  • (I) C30H35N4O4+.Cl-, Mr = 551.07, triclinic, P1, a = 10.512 (2), b = 11.203 (2), c = 14.469 (2) A, alpha = 111.49 (1), beta = 105.74 (1), gamma = 95.82 (1) degrees, V = 1487.4 (4) A3, Z = 2, Dm = 1.23 (by flotation), Dx = 1.231 g cm-3, lambda(Cu K alpha) = 1.5418 A, mu = 14.68 cm-1, F(000) = 584, T = 296 K, R = 0.109 for 3100 unique reflections with I greater than 3 sigma(I). (II) C26H26N3O4+.Cl-.H2O, Mr = 497.98, triclinic, P1, a = 9.4810 (8), b = 14.495 (2), c = 9.255 (1) A, alpha = 95.48 (1), beta = 98.17 (1), gamma = 101.78 (1) degrees, V = 1222.3 (5) A3, Z = 2, Dm = 1.35 (by flotation), Dx = 1.353 g cm-3, lambda(Cu K alpha) = 1.5418 A, mu = 17.34 cm-1, F(000) = 524, T = 296 K, R = 0.052 for 3589 unique reflections with I greater than 3 sigma(I).
  • [MeSH-major] Aminoacridines / chemistry. DNA / metabolism. Nitrobenzoates / chemistry. Proflavine / analogs & derivatives. Ultraviolet Rays
  • [MeSH-minor] Chemistry, Physical. Crystallization. Molecular Structure. Photochemistry. Physicochemical Phenomena. X-Ray Diffraction

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  • (PMID = 1610529.001).
  • [ISSN] 0108-2701
  • [Journal-full-title] Acta crystallographica. Section C, Crystal structure communications
  • [ISO-abbreviation] Acta Crystallogr C
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] DENMARK
  • [Chemical-registry-number] 0 / Aminoacridines; 0 / Nitrobenzoates; 140866-76-8 / 3,6-bis(dimethylamino)-10-(6-(4-nitrobenzoyloxy)hexyl)acridinium; 140866-77-9 / 9-((6-(4-nitrobenzoyloxy)hexyl)amino)acridine; 9007-49-2 / DNA; CY3RNB3K4T / Proflavine
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67. Wong YL, Hubieki MP, Curfman CL, Doncel GF, Dudding TC, Savle PS, Gandour RD: A structure-activity study of spermicidal and anti-HIV properties of hydroxylated cationic surfactants. Bioorg Med Chem; 2002 Nov;10(11):3599-608
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The syntheses of 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethylhexadecan-1-aminium chloride [1(16)Cl] and iodide [1(16)I], 2-hydroxy-N,N,N-trimethylhexadecan-1-aminium chloride (6), N-(2-hydroxyethyl)-N,N-dimethylhexadecan-1-aminium chloride (8), N,N-bis(2-hydroxyethyl)-N-methylhexadecan-1-aminium chloride (11), and 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-4-oxahexadecan-1-aminium chloride (14) are reported along with the critical micelle concentrations (cmcs), as measured by conductivity at 25 degrees C, of 1(16)Cl, 1(16)I, 6, 8, 11, and N,N,N-trimethylhexadecan-1-aminium chloride (12).
  • A plot of minimum effective concentration (MEC) in the Sander-Cramer spermicidal assay and cmc shows that 1(16)Cl and 6 have the best spermicidal activity and highest cmcs.
  • Compounds 8, 11, and 1(16)Cl are the most active at 0.05 mg mL(-1) against cell-free and cell-associated virus.
  • In conclusion, 1(16)Cl shows the best combination of dual activity against sperm and HIV; it is a promising candidate for further preclinical studies as a topical, contraceptive microbicide.
  • [MeSH-major] Anti-HIV Agents / chemistry. Anti-HIV Agents / pharmacology. Spermatocidal Agents / chemistry. Spermatocidal Agents / pharmacology. Surface-Active Agents / chemistry. Surface-Active Agents / pharmacology
  • [MeSH-minor] Cations. Chemistry, Physical. HIV-1 / drug effects. Humans. Hydroxylation. In Vitro Techniques. Indicators and Reagents. Male. Micelles. Microbial Sensitivity Tests. Oxygen / chemistry. Physicochemical Phenomena. Structure-Activity Relationship

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  • (PMID = 12213475.001).
  • [ISSN] 0968-0896
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-HIV Agents; 0 / Cations; 0 / Indicators and Reagents; 0 / Micelles; 0 / Spermatocidal Agents; 0 / Surface-Active Agents; S88TT14065 / Oxygen
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68. Korshunov AP, Suntsov VG, Pitaeva AN, Toropov VN, Doronin VP: [The physicochemical aspects of ion transport across dental enamel]. Stomatologiia (Mosk); 2000;79(4):6-8
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  • [Title] [The physicochemical aspects of ion transport across dental enamel].
  • [Transliterated title] Fiziko-khimicheskie aspekty transporta ionov cherez émal' zuba.
  • Passive transport of K+, Na+ Ca2+, Cl-, and F- ions through dental enamel was studied with due consideration for its porous structure.
  • The size of pores allows penetration of large molecules and ions through the enamel.
  • [MeSH-minor] Animals. Chemistry, Physical. Cuspid. Diffusion. In Vitro Techniques. Ion Transport. Physicochemical Phenomena. Porosity. Swine

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  • (PMID = 10961103.001).
  • [ISSN] 0039-1735
  • [Journal-full-title] Stomatologii︠a︡
  • [ISO-abbreviation] Stomatologiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] RUSSIA
  • [Chemical-registry-number] 0 / Electrolytes
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69. Ye WP, Chien YW: Dual-controlled drug delivery across biodegradable copolymer. I. Delivery kinetics of levonorgestrel and estradiol through (caprolactone/lactide) block copolymer. Pharm Dev Technol; 1996 Apr;1(1):1-9
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  • Four block copolymers of caprolactone (CL) and dl-lactide (LA) with varying weight fractions were synthesized by living polymerization in the presence of Al/Zn bimetallic alkoxide complex.
  • The solubility of levonorgestrel (LNG) and estradiol (E2) in the copolymers was evaluated and found to increase exponentially with CL mole fraction.
  • Their aqueous solubilities were also studied and observed to increase linearly with the concentration of benzalkonium chloride (BAC), a solubilizer.
  • Permeation rates and release fluxes at steady state as well as the permeability and solubility of LNG and E2 in the copolymers suggest that these permeation parameters are affected by copolymer composition, which increase as the CL/LA ratio in the copolymer was increased.
  • [MeSH-minor] Biotransformation. Chemistry, Physical. Chromatography, High Pressure Liquid. Diffusion. Permeability. Physicochemical Phenomena. Solubility

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  • (PMID = 9552325.001).
  • [ISSN] 1083-7450
  • [Journal-full-title] Pharmaceutical development and technology
  • [ISO-abbreviation] Pharm Dev Technol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Contraceptive Agents, Female; 0 / Polyesters; 4TI98Z838E / Estradiol; 5W7SIA7YZW / Levonorgestrel; 70524-20-8 / lactide-caprolactone copolymer
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70. Kim Y, Cuff GW, Morris RM: Effect of chloride ion on the sedimentation volume and zeta potential of zinc insulin suspensions in neutral pH range. J Pharm Sci; 1995 Jun;84(6):755-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of chloride ion on the sedimentation volume and zeta potential of zinc insulin suspensions in neutral pH range.
  • When zinc insulin suspensions of different pH values were prepared in the presence of sodium chloride, an unusually high sedimentation volume was found at about pH 6.9.
  • An experimental investigation was conducted in an effort to understand this phenomenon.
  • The experiments involved measurements of electrophoretic mobilities to calculate zeta potentials and sedimentation volumes of zinc insulin suspensions prepared at different NaCl concentrations (0, 17, and 120 mM) and at various pH values from 5 to 8.
  • The general trend observed was that the magnitude of the zeta potential increased with pH when it was higher than the isoelectric point of 5.3.
  • When the sodium chloride concentration was 120 mM, a very rapid change in zeta potential was observed in the pH range of 6.6 to 7.2, with a maximum magnitude of zeta potential at about pH 6.9, the same pH that was observed to yield the largest sedimentation volume.
  • Our experimental results indicate that the greatest adsorption of chloride ion on the zinc insulin suspension particles occurred in the same pH range, which appeared to be responsible for the rapid change of zeta potential in that pH range.
  • [MeSH-major] Chlorides / chemistry. Insulin / chemistry
  • [MeSH-minor] Chemistry, Physical. Electric Conductivity. Electrophoresis, Polyacrylamide Gel. Humans. Hydrogen-Ion Concentration. Isoelectric Focusing. Physicochemical Phenomena

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  • (PMID = 7562418.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Chlorides; 0 / Insulin
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71. Cannon JB, Krill SL, Porter WR: Physicochemical properties of A-75998, an antagonist of luteinizing hormone releasing hormone. J Pharm Sci; 1995 Aug;84(8):953-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physicochemical properties of A-75998, an antagonist of luteinizing hormone releasing hormone.
  • The physicochemical properties of A-75998, a synthetic antagonist of luteinizing hormone releasing hormone with potential for treatment of hormone-sensitive cancers and endometriosis, are described.
  • An accelerated solution stability study indicated that the compound is relatively stable and showed a U-shaped pH-rate profile, with maximum stability between pH 4.5 and 6.5.
  • The acid dissociation behavior of A-75998 was examined by UV-visible spectrophotometry at 25 degrees C in a series of buffers ranging from pH 1 to 13.
  • The apparent n-octanol/water partition coefficients were measured from pH 2 to 13, and the profile was consistent with the expected acid-dissociation behavior.
  • While appearing fairly water-soluble at pH < 5, dynamic light scattering of A-75998 in pH 4.5 buffer indicated the formation of aggregates of nonuniform size distribution.
  • A-75998 exhibited reverse or thermal gelation; sodium chloride exacerbates this gel formation and self-association.
  • Surface activity was pH-dependent, but no evidence was found for micelle formation.
  • [MeSH-major] Gonadotropin-Releasing Hormone / antagonists & inhibitors. Oligopeptides / chemistry
  • [MeSH-minor] Chemistry, Physical. Chromatography, High Pressure Liquid. Densitometry. Hydrogen-Ion Concentration. Light. Molecular Weight. Particle Size. Physicochemical Phenomena. Scattering, Radiation. Solubility. Surface Tension

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  • (PMID = 7500280.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / A 75998; 0 / Oligopeptides; 33515-09-2 / Gonadotropin-Releasing Hormone
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72. Teagarden DL, Radavich JF, White JL, Hem SL: Aluminum chlorohydrate II: Physicochemical properties. J Pharm Sci; 1981 Jul;70(7):762-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aluminum chlorohydrate II: Physicochemical properties.
  • Determination of the chloride content of aluminum chlorohydrate by a chloride-selective indicated that gamma Cl leads to 1.
  • IR analysis demonstrated that chloride was exchanged readily by nitrate and that the IR bands of the anion were not perturbed significantly.
  • Thus, chloride is believed to act as a counterion.
  • A high positive charge is predicted based o the critical coagulation concentration of aluminum chlorohydrate and the stability of aluminum chlorohydrate to attack by protons, as demonstrated by pH-stat titration Potentiometric titration with sodium hydroxide showed adsorption of hydroxyl anions initially, but a higher pH than expected was observed at the end-point.
  • [MeSH-minor] Chemistry, Physical. Crystallization. Electrochemistry. Hydrogen-Ion Concentration. Microscopy, Electron, Scanning. Physicochemical Phenomena. Potentiometry

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  • (PMID = 7264922.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 5QB0T2IUN0 / Aluminum Hydroxide; HPN8MZW13M / aluminum chlorhydrate
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73. Spier F, Zavareze Eda R, Marques e Silva R, Elias MC, Dias AR: Effect of alkali and oxidative treatments on the physicochemical, pasting, thermal and morphological properties of corn starch. J Sci Food Agric; 2013 Jul;93(9):2331-7
Hazardous Substances Data Bank. SODIUM HYPOCHLORITE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of alkali and oxidative treatments on the physicochemical, pasting, thermal and morphological properties of corn starch.
  • Thus this work evaluated the physicochemical, pasting, morphological, cystallinity and thermal properties of chemically modified corn starch, after either the isolated or combined action of alkaline (sodium hydroxide) and oxidative (sodium hypochlorite) treatments.
  • RESULTS: The highest values for the sum of carbonyl and carboxyl and enzymatic hydrolysis occurred in starches submitted to oxidative treatment at high active chlorine concentrations.
  • [MeSH-major] Caustics / chemistry. Food Handling. Oxidants / chemistry. Seeds / chemistry. Starch / chemistry. Zea mays / chemistry
  • [MeSH-minor] Crystallization. Gels. Hot Temperature. Hydrolysis. Microscopy, Electron, Scanning. Osmolar Concentration. Oxidation-Reduction. Physicochemical Phenomena. Sodium Hydroxide / chemistry. Sodium Hypochlorite / chemistry. Suspensions. Transition Temperature. Viscosity

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  • [Copyright] © 2013 Society of Chemical Industry.
  • (PMID = 23423960.001).
  • [ISSN] 1097-0010
  • [Journal-full-title] Journal of the science of food and agriculture
  • [ISO-abbreviation] J. Sci. Food Agric.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Caustics; 0 / Gels; 0 / Oxidants; 0 / Suspensions; 55X04QC32I / Sodium Hydroxide; 9005-25-8 / Starch; DY38VHM5OD / Sodium Hypochlorite
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74. Abezgauz L, Kuperkar K, Hassan PA, Ramon O, Bahadur P, Danino D: Effect of Hofmeister anions on micellization and micellar growth of the surfactant cetylpyridinium chloride. J Colloid Interface Sci; 2010 Feb 1;342(1):83-92
Hazardous Substances Data Bank. SODIUM CHLORATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of Hofmeister anions on micellization and micellar growth of the surfactant cetylpyridinium chloride.
  • In this work we study how monovalent anions of the lyotropic series affect micellization, micellar transitions, and micellar growth of the cationic surfactant N-cetyl pyridinium chloride (CPyCl), with the aim of achieving a tool to methodically tune these self-assembly characteristics.
  • For the first time, a set of ions of the Hofmeister series were studied by combining indirect (surface tension, conductivity, optical absorption, viscosity, dynamic light scattering) and direct-imaging cryogenic-transmission electron microscopy (cryo-TEM).
  • Following recent literature on anionic surfactants, we considered the pyridinium headgroup as a chaotropic cation, interacting with cosmotrope and chaotrope anions (Cl(-), Br(-), NO(3)(-), ClO(3)(-)).
  • Especially interesting was the relatively small effect of the chlorate ion on the CMC, but its large effect on micellar transition and growth.
  • [MeSH-major] Anions / chemistry. Cetylpyridinium / chemistry. Micelles. Surface-Active Agents / chemistry
  • [MeSH-minor] Bromides / chemistry. Chlorates / chemistry. Cryoelectron Microscopy. Microscopy, Electron, Transmission. Nitrates / chemistry. Physicochemical Phenomena. Sodium Chloride / chemistry. Sodium Compounds / chemistry. Sodium Salicylate / chemistry. Surface Tension

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  • [Copyright] Copyright 2009 Elsevier Inc. All rights reserved.
  • (PMID = 19939405.001).
  • [ISSN] 1095-7103
  • [Journal-full-title] Journal of colloid and interface science
  • [ISO-abbreviation] J Colloid Interface Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anions; 0 / Bromides; 0 / Chlorates; 0 / Micelles; 0 / Nitrates; 0 / Sodium Compounds; 0 / Surface-Active Agents; 451W47IQ8X / Sodium Chloride; 8M4L3H2ZVZ / sodium nitrate; CUB7JI0JV3 / Cetylpyridinium; LC1V549NOM / sodium bromide; T95DR77GMR / sodium chlorate; WIQ1H85SYP / Sodium Salicylate
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75. Zaghloul M, Prakash V: Effect of succinylation on the functional and physicochemical properties of alpha-globulin, the major protein fraction from Sesamum indicum L. Nahrung; 2002 Oct;46(5):364-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of succinylation on the functional and physicochemical properties of alpha-globulin, the major protein fraction from Sesamum indicum L.
  • alpha-Globulin the major protein fraction from Sesamum indicum was succinylated to different levels and the effect of the chemical modification was evaluated both on the functional and physicochemical properties.
  • The results suggest that the pH of minimum solubility shifted to the more acidic side (pH approximately 4.5-5.5) for the succinylated alpha-globulin whereas for control alpha-globulin the pH of minimum solubility was 6.5.
  • Bulk density, water absorption capacity, oil absorption capacity, foam capacity and foam stability were evaluated in phosphate buffer (pH 7.0) containing 0.5 M sodium chloride and all these properties showed increased values as a result of succinylation.
  • [MeSH-major] Alpha-Globulins / analysis. Plant Proteins / analysis. Sesamum / chemistry. Succinates / chemistry
  • [MeSH-minor] Chemistry, Physical. Drug Stability. Emulsions. Hydrogen-Ion Concentration. Physicochemical Phenomena. Solubility. Spectrometry, Fluorescence. Temperature. Ultracentrifugation

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  • (PMID = 12428456.001).
  • [ISSN] 0027-769X
  • [Journal-full-title] Die Nahrung
  • [ISO-abbreviation] Nahrung
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Alpha-Globulins; 0 / Emulsions; 0 / Plant Proteins; 0 / Succinates
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76. Xu H, Ding P, Wei G, Zheng J: Preparation and some physicochemical properties of cross-linked poloxamer hydrogel spheres. Drug Dev Ind Pharm; 2001 Feb;27(2):171-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preparation and some physicochemical properties of cross-linked poloxamer hydrogel spheres.
  • The principal purpose of this paper is to report the preparation of cross-linked poloxamer hydrogel spheres in an aqueous two-phase system without the use of organic solvent and additional emulsifier and physicochemical properties related to drug release.
  • Poloxamer 188 was modified with methacryloyl chloride to obtain the polymerizable derivative (macromer).
  • [MeSH-major] Hydrogels / chemistry. Microspheres. Poloxamer / chemistry
  • [MeSH-minor] Chemistry, Physical. Cross-Linking Reagents. Magnetic Resonance Spectroscopy. Microscopy, Electron, Scanning. Particle Size. Physicochemical Phenomena. Spectrophotometry, Ultraviolet. Spectroscopy, Fourier Transform Infrared. Vitamin B 12 / chemistry

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  • (PMID = 11266229.001).
  • [ISSN] 0363-9045
  • [Journal-full-title] Drug development and industrial pharmacy
  • [ISO-abbreviation] Drug Dev Ind Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cross-Linking Reagents; 0 / Hydrogels; 106392-12-5 / Poloxamer; P6YC3EG204 / Vitamin B 12
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77. Braiman MS, Walter TJ, Briercheck DM: Infrared spectroscopic detection of light-induced change in chloride-arginine interaction in halorhodopsin. Biochemistry; 1994 Feb 22;33(7):1629-35
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  • [Title] Infrared spectroscopic detection of light-induced change in chloride-arginine interaction in halorhodopsin.
  • A light-induced transient change in the ionic interaction between chloride and arginine in the transmembrane anion pump halorhodopsin (hR) is detected with infrared absorption spectroscopy.
  • In the IR difference spectrum of hR and one of its photoproducts (hL), only a few bands have frequencies that depend on the particular halide ion (Cl-, Br-, or I-) present.
  • We conclude that a halide-arginine ion pair is present in the hR state; this interaction appears to be disrupted by photoconversion to hL.
  • [MeSH-major] Arginine / chemistry. Bacteriorhodopsins / chemistry. Chlorides / chemistry. Light. Spectroscopy, Fourier Transform Infrared
  • [MeSH-minor] Anions. Bromides / pharmacology. Chemistry, Physical. Electrochemistry. Guanidine. Guanidines / chemistry. Halorhodopsins. Iodides / pharmacology. Models, Molecular. Physicochemical Phenomena

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  • (PMID = 8110765.001).
  • [ISSN] 0006-2960
  • [Journal-full-title] Biochemistry
  • [ISO-abbreviation] Biochemistry
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM46851
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Anions; 0 / Bromides; 0 / Chlorides; 0 / Guanidines; 0 / Halorhodopsins; 0 / Iodides; 53026-44-1 / Bacteriorhodopsins; 94ZLA3W45F / Arginine; JU58VJ6Y3B / Guanidine
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78. Duszyk M, Liu D, French AS, Man SF: Halide permeation through three types of epithelial anion channels after reconstitution into giant liposomes. Eur Biophys J; 1993;22(1):5-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ion channels were characterized using the excised inside-out patch clamp configuration.
  • The linear 20 pS Cl- channel had the halide permeability sequence Cl- > I- > or = Br- > F-, and showed anomalous mole-fraction behavior in solutions containing different proportions of Cl- and F- ions.
  • The autwardly rectifying Cl- channel had the halide permeability sequence I- > Br- > Cl- > F-, and also showed anomalous mole-fraction behavior, indicating that both these channels probably contain multi-ion pores.
  • It was not selective amongst the halides, and there was no deviation from a linear dependence of relative current on molar fractions, indicating relatively simple permeation through the pore.
  • Comparison with the chloride channel proteins isolated biochemically from epithelial cell membranes is discussed.
  • [MeSH-major] Halogens / pharmacokinetics. Ion Channels / metabolism. Liposomes
  • [MeSH-minor] Cell Membrane Permeability / physiology. Chemistry, Physical. Chloride Channels. Epithelium / metabolism. Humans. Membrane Proteins / chemistry. Membrane Proteins / metabolism. Membrane Proteins / physiology. Pancreatic Neoplasms / metabolism. Physicochemical Phenomena. Tumor Cells, Cultured

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  • (PMID = 7685690.001).
  • [ISSN] 0175-7571
  • [Journal-full-title] European biophysics journal : EBJ
  • [ISO-abbreviation] Eur. Biophys. J.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] GERMANY
  • [Chemical-registry-number] 0 / Chloride Channels; 0 / Halogens; 0 / Ion Channels; 0 / Liposomes; 0 / Membrane Proteins
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79. Boumaiza M: [The limnology of Tunisia: physicochemical study]. Arch Inst Pasteur Tunis; 1984 Jun-Sep;61(2-3):205-46

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  • [Title] [The limnology of Tunisia: physicochemical study].
  • [Transliterated title] Contribution à la limnologie de la Tunisie: étude physico-chimique.
  • Several chemical and physical parameters are measured in forty seven stations, distributed on the most part of the hydrographic systems of Tunisia.
  • Some parameters: temperature of the water (T), salinity (S, electric conductivity (CE), chloride (Cl-), total hardness (DT) and turbidity (TUR) show great variations in the Northern hydrographic systems.
  • In these systems, the parameters (S, CE, Cl-, DT) are generally elevated in the tributaries of the south bank of the Medjerda, the North-East streams, Melah and Tine Streams which flow in the Ichkeul lake.
  • [MeSH-minor] Chemistry, Physical. Chlorides / analysis. Electric Conductivity. Minerals / analysis. Physicochemical Phenomena. Temperature. Tunisia

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  • (PMID = 6544054.001).
  • [ISSN] 0020-2509
  • [Journal-full-title] Archives de l'Institut Pasteur de Tunis
  • [ISO-abbreviation] Arch Inst Pasteur Tunis
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] TUNISIA
  • [Chemical-registry-number] 0 / Chlorides; 0 / Minerals
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80. Niu M, Zhang W, Wang D, Chen Y, Chen R: Correlation of physicochemical properties and sludge dewaterability under chemical conditioning using inorganic coagulants. Bioresour Technol; 2013 Sep;144:337-43
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  • [Title] Correlation of physicochemical properties and sludge dewaterability under chemical conditioning using inorganic coagulants.
  • This study investigated the effects of chemical conditioning with three representative inorganic coagulants (FeCl3, polyaluminum chloride (PACl) and high performance PACl (HPAC) on sludge dewaterability.
  • We monitored the particle size, kinetic viscosity (KV), fractal dimension (D(F)) and extracellular polymeric substances (EPS) located in different layers of sludge floc (soluble, loosely-bound (LB), tightly-bound (TB)) to understand the correlation of dewaterability and physicochemical properties of sludge under chemical conditioning.
  • Furthermore, sludge dewaterability correlated well with the change in concentration of soluble EPS, LB-EPS and TB-EPS, but not with KV, D(F), floc size.
  • [MeSH-major] Inorganic Chemicals / chemistry. Physicochemical Phenomena. Sewage / chemistry. Water / chemistry
  • [MeSH-minor] Biopolymers / chemistry. Filtration. Flocculation. Kinetics. Molecular Weight. Particle Size. Solubility. Viscosity

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  • [Copyright] Copyright © 2013. Published by Elsevier Ltd.
  • (PMID = 23886852.001).
  • [ISSN] 1873-2976
  • [Journal-full-title] Bioresource technology
  • [ISO-abbreviation] Bioresour. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biopolymers; 0 / Inorganic Chemicals; 0 / Sewage; 059QF0KO0R / Water
  • [Keywords] NOTNLM ; Chemical conditioning / EPS / Inorganic coagulants / Physicochemical properties / Sludge dewaterability
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86. Badawi HM: Vibrational analyses of sulfamoyl halides NH2SO2X (X is F, Cl and Br). Spectrochim Acta A Mol Biomol Spectrosc; 2006 Oct;65(2):453-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vibrational analyses of sulfamoyl halides NH2SO2X (X is F, Cl and Br).
  • The structural stability of sulfamoyl halides NH(2)-SO(2)X (X is F, Cl and Br) were investigated by DFT-B3LYP/6-311+G** and ab initio MP2/6-311+G** calculations.
  • [MeSH-major] Mafenide / analogs & derivatives. Mafenide / chemistry. Spectroscopy, Fourier Transform Infrared. Spectrum Analysis, Raman
  • [MeSH-minor] Chemistry, Physical. Molecular Conformation. Normal Distribution. Physicochemical Phenomena. Quantum Theory. Vibration

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  • (PMID = 16530000.001).
  • [ISSN] 1386-1425
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 58447S8P4L / Mafenide
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87. Choi H, Lee M, Kim M, Kim C: Effect of additives on the physicochemical properties of liquid suppository bases. Int J Pharm; 1999 Nov 10;190(1):13-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of additives on the physicochemical properties of liquid suppository bases.
  • To investigate the effects of additives on the physicochemical properties of in situ gelling and mucoadhesive liquid suppository base, gelation temperature, gel strength and bioadhesive force of liquid suppository base, poloxamer 407 (P 407) and poloxamer 188 (P 188) (15/15%) were evaluated in the presence of following additives: solvent (ethanol, propylene glycol, glycerin), ionic strength-controlling agent (sodium chloride) and pH-controlling agent (hydrochloric acid, sodium monohydrogen phosphate, sodium dihydrogen phosphate).
  • Among the additives studied, sodium chloride, sodium monohydrogen phosphate and sodium dihydrogen phosphate increased to a great extent the gel strength and the bioadhesive force of P 407/P 188 (15/15%) with a decrease in gelation temperature.
  • However, the addition of 1% of sodium chloride, sodium monohydrogen phosphate or sodium dihydrogen phosphate caused a greater than 60-fold increase in gel strength and over a tenfold increase in bioadhesive force with 2-4 degrees C decrease of gelation temperature within optimal range, compared with P 407/P 188 (15/15%) alone.
  • Taken together, these findings indicate that the effect of additives on the physicochemical properties of liquid suppository bases depends on their bonding capacities, in that additives such as sodium chloride, sodium monohydrogen phosphate and sodium dihydrogen phosphate having strong cross-linking bonds with the components of liquid suppository base increase the strength and bioadhesive force of a gel compared to liquid suppository base alone, while additives such as ethanol, propylene glycol and hydrochloric acid having weaker hydrogen bonding result in a weaker response.
  • Thus, sodium chloride and sodium phosphates appear to be promising additives for in situ gelling and mucoadhesive liquid suppository base, if used in adequate amounts.
  • [MeSH-major] Solvents / chemistry. Suppositories / chemistry
  • [MeSH-minor] Adhesiveness. Chemistry, Physical. Drug Compounding. Ethanol / chemistry. Gels. Glycerol / chemistry. Hydrochloric Acid / chemistry. Hydrogen-Ion Concentration. Osmolar Concentration. Phosphates / chemistry. Physicochemical Phenomena. Poloxamer / chemistry. Propylene Glycol / chemistry. Sodium Chloride / chemistry. Temperature

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  • (PMID = 10528092.001).
  • [ISSN] 0378-5173
  • [Journal-full-title] International journal of pharmaceutics
  • [ISO-abbreviation] Int J Pharm
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Gels; 0 / Phosphates; 0 / Solvents; 0 / Suppositories; 106392-12-5 / Poloxamer; 3K9958V90M / Ethanol; 451W47IQ8X / Sodium Chloride; 6DC9Q167V3 / Propylene Glycol; PDC6A3C0OX / Glycerol; QTT17582CB / Hydrochloric Acid; SE337SVY37 / sodium phosphate
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88. Strietzel R, Hösch A, Kalbfleisch H, Buch D: In vitro corrosion of titanium. Biomaterials; 1998 Aug;19(16):1495-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Titanium is used in dentistry for implants and frame work because of its sufficient chemical, physical and biological properties.
  • The following parameters were investigated: specimen preparation, grinding, pH-value, different casting systems, comparison with CAD/CAM, influence of: chloride, thiocyanate, fluoride, lactate, citrate, oxalate, acetate.
  • Titanium reveals ion releases [(0.01-0.1) microg/(cm2 x d)] in the magnitude of gold alloys.
  • There is little influence of grinding and casting systems in comparison with organic acids or pH value.
  • The ion release increases extreme (up to 500 microg/(cm2 x d)) in the presence of fluoride.
  • Low pH values accelerate this effect even more.
  • [MeSH-major] Biocompatible Materials / chemistry. Titanium / chemistry
  • [MeSH-minor] Anions. Chemistry, Physical. Computer-Aided Design. Corrosion. Physicochemical Phenomena

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  • (PMID = 9794525.001).
  • [ISSN] 0142-9612
  • [Journal-full-title] Biomaterials
  • [ISO-abbreviation] Biomaterials
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Anions; 0 / Biocompatible Materials; D1JT611TNE / Titanium
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89. Dorneanu M, Stefănescu E, Păduraru O, Pavelescu M, Hriscu A: [The reaction of 3-(R-phenyl)-6-hydrazine pyridazine with 5-methylisatin and 1-morpholinomethyl-5-methylisatin]. Rev Med Chir Soc Med Nat Iasi; 1996 Jan-Jun;100(1-2):167-71
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  • [Transliterated title] La réaction de la 3-(R-phényle)-6-hydrazino-pyridazine avec la 5-méthyl-isatine et la 1-morpholinométhyl-5-méthyl-isatine.
  • This paper presents the synthesis of six hydrazones obtained by treating 5-methyl-isatin or 1-morpholino methyl-5-methyl-isatin with 3-(R-phenyl)-6-hydrazino-pyridazine (R = OCH3, Cl, Br) and two complex combination with copper, derived from 3-(p-anisyl-pyridazinyl)-hydrazone-5-methyl-indoline-2- one.
  • [MeSH-major] Anti-Infective Agents / chemical synthesis. Anti-Inflammatory Agents / chemical synthesis. Hydrazines / chemistry. Hydrazones / chemical synthesis. Isatin / analogs & derivatives. Pyridazines / chemistry
  • [MeSH-minor] Animals. Anti-Bacterial Agents. Candida albicans / drug effects. Carrageenan. Chemistry, Physical. Drug Evaluation, Preclinical. Escherichia coli / drug effects. Inflammation / chemically induced. Inflammation / drug therapy. Mice. Physicochemical Phenomena. Staphylococcus aureus / drug effects. Structure-Activity Relationship

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  • (PMID = 9455421.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] ROMANIA
  • [Chemical-registry-number] 0 / 1-morpholinomethyl-5-methylisatin; 0 / 3-phenyl-6-hydrazinopyridazine; 0 / Anti-Bacterial Agents; 0 / Anti-Infective Agents; 0 / Anti-Inflammatory Agents; 0 / Hydrazines; 0 / Hydrazones; 0 / Pyridazines; 608-05-9 / 5-methylisatin; 82X95S7M06 / Isatin; 9000-07-1 / Carrageenan
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90. Kataky R, Parker D: Sensitive and specific electrochemical sensors for charge-diffuse cations: use of lipophilic cyclodextrins and an enzyme relay for the determination of acetylcholine. Analyst; 1996 Dec;121(12):1829-34
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  • The application of lipophilic beta-CDs as ionophores for sensing acetylcholine chloride using a potentiometric ISE and an amperometric biosensor is described.
  • [MeSH-major] Acetylcholine / analysis. Biosensing Techniques. Cations / chemistry. Cyclodextrins / chemistry. Enzymes, Immobilized
  • [MeSH-minor] Acetylcholinesterase / chemistry. Animals. Cattle. Chemistry, Physical. Electrochemistry. Physicochemical Phenomena

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  • (PMID = 9008405.001).
  • [ISSN] 0003-2654
  • [Journal-full-title] The Analyst
  • [ISO-abbreviation] Analyst
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Cations; 0 / Cyclodextrins; 0 / Enzymes, Immobilized; EC 3.1.1.7 / Acetylcholinesterase; N9YNS0M02X / Acetylcholine
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91. Ananyev GM, Dismukes GC: High-resolution kinetic studies of the reassembly of the tetra-manganese cluster of photosynthetic water oxidation: proton equilibrium, cations, and electrostatics. Biochemistry; 1996 Nov 19;35(46):14608-17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two distinct mechanisms appear to be involved: binding to one or both of the first two Mn(2+)-specific sites and screening of negative charges on apo-WOC that are responsible for concentrating Mn2+ ions by electrostatic steering;.
  • (2) the Michaelis constant for the calcium requirement for Yss at sufficiently low Mn2+ concentrations (8 microM) that competition at the calcium site does not occur is K(m) = 1.4 mM.
  • Numerically, K(m) is the same for reactivation of O2 evolution in Ca-depleted PSII membranes which retain four Mn ions;.
  • (3) in the absence of Ca2+ but in the presence of saturating amounts of Mn2+ (8 Mn/apo-WOC) and Cl-(35 mM) assembly of a stable tetra-Mn cluster occurs neither under illumination nor in the dark after subsequent addition of CaCl2.
  • (4) protons in equilibrium with the buffer greatly increase the half-time 3-fold between pH 6.75 and 5.4, indicating ionization of one or more protons from the first photo-oxidized intermediate formed prior to the rate-limiting step (photo-oxidation of the second Mn2+);.
  • [MeSH-minor] Benzylamines / metabolism. Chemistry, Physical. Kinetics. Oxidation-Reduction. Physicochemical Phenomena. Propionates / metabolism. Static Electricity

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  • Hazardous Substances Data Bank. MAGNESIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. MANGANESE, ELEMENTAL .
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  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. OXYGEN .
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  • (PMID = 8931559.001).
  • [ISSN] 0006-2960
  • [Journal-full-title] Biochemistry
  • [ISO-abbreviation] Biochemistry
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM39932
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Benzylamines; 0 / N,N,N',N'-tetrapropionato-1,3-bis(aminomethyl)benzene; 0 / Propionates; 42Z2K6ZL8P / Manganese; 9NEZ333N27 / Sodium; I38ZP9992A / Magnesium; S88TT14065 / Oxygen; SY7Q814VUP / Calcium
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92. Frydenvang K, Jensen B: Conformational analysis of acetylcholine and related choline esters. Acta Crystallogr B; 1996 Feb 1;52 ( Pt 1):184-93
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  • The crystal structures of carbamoylcholine [2-(carbamoyloxy)-N,N,N-trimethylethanaminium] chloride, bromide and iodide, methoxycarbonylcholine [2-(methoxycarbonyloxy)-N,N,N-trimethylethanaminium] iodide, acetylcholine [2-(acetyloxy)-N,N,N-trimethylethanaminium] chloride and succinylcholine ¿2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis(N,N,N-trimethylet hanaminium)¿ iodide have been redetermined at 105 K in order to obtain detailed and accurate information on the geometry of choline esters and to elucidate the conformationally dependent changes of geometry.
  • The usefulness of molecular mechanics calculations for quaternary ammonium ions is discussed.
  • [MeSH-major] Acetylcholine / chemistry. Carbachol / chemistry. Choline / analogs & derivatives. Succinylcholine / chemistry
  • [MeSH-minor] Chemistry, Physical. Crystallization. Crystallography, X-Ray. Hydrogen Bonding. Models, Molecular. Molecular Conformation. Physicochemical Phenomena. Thermodynamics

  • Hazardous Substances Data Bank. SUCCINYLCHOLINE .
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  • (PMID = 8907583.001).
  • [ISSN] 0108-7681
  • [Journal-full-title] Acta crystallographica. Section B, Structural science
  • [ISO-abbreviation] Acta Crystallogr., B
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] DENMARK
  • [Chemical-registry-number] 70384-36-0 / methoxycarbonylcholine; 8Y164V895Y / Carbachol; J2R869A8YF / Succinylcholine; N91BDP6H0X / Choline; N9YNS0M02X / Acetylcholine
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93. Lefevre C, Kang HC, Haugland RP, Malekzadeh N, Arttamangkul S, Haugland RP: Texas Res-X and rhodamine Red-X, new derivatives of sulforhodamine 101 and lissamine rhodamine B with improved labeling and fluorescence properties. Bioconjug Chem; 1996 Jul-Aug;7(4):482-9
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  • Texas Red sulfonyl chloride (TR-SC) and Lissamine rhodamine B sulfonyl chloride (LRB-SC) are popular dyes often used to prepare red fluorescent conjugates that are useful second labels in combination with fluorescein.
  • Unfortunately, being sulfonyl chloride derivatives, both are unstable to moisture during storage and prone to hydrolysis in the conjugation reaction.
  • Their instability causes the percentage of reactive dye to vary from lot to lot and requires use of low temperatures and a relatively high pH to optimize conjugation efficiency.
  • Their spectral properties are similar to those of their sulfonyl chloride analogs; moreover, incorporation of the succinimidyl ester at the end of the aliphatic chain spacer facilitates conjugation, decreases precipitation of proteins during conjugation and storage, and usually increases the fluorescence yield of the conjugate.
  • The reactivity of both new derivatives is high between pH 7.5 and 8.5, allowing conjugation of proteins that do not tolerate the high pH required for reaction with sulfonyl chlorides.
  • [MeSH-major] Coloring Agents / chemical synthesis. Rhodamines / chemical synthesis. Rhodamines / chemistry
  • [MeSH-minor] Chemistry, Physical. Fluorescence. Physicochemical Phenomena. Solutions

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  • (PMID = 8853462.001).
  • [ISSN] 1043-1802
  • [Journal-full-title] Bioconjugate chemistry
  • [ISO-abbreviation] Bioconjug. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Rhodamines; 0 / Solutions; 0 / Texas Red-X succinimidyl ester; 0 / rhodamine red-X succinimidyl ester; 2609-88-3 / lissamine rhodamine B; 60311-02-6 / sulforhodamine 101
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94. Takruri H, Ecanow B, Balagot R: Water as a nonpolar partition medium. J Pharm Sci; 1977 Feb;66(2):283-4
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  • The partition coefficients of theobromine and theophylline in gelatin-benzalkonium chloride coacervate systems were also found to correlate with the partition values reported in the literature for heptane-water and chloroform-water systems.
  • [MeSH-minor] Animals. Barbiturates / metabolism. Chemistry, Pharmaceutical. Chemistry, Physical. Colon / metabolism. Intestinal Absorption. Physicochemical Phenomena. Rats. Theobromine / metabolism. Theophylline / metabolism

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  • (PMID = 839434.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Barbiturates; 059QF0KO0R / Water; C137DTR5RG / Theophylline; OBD445WZ5P / Theobromine
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95. Tokumura T, Machida R, Tsuchiya Y, Sasaki A, Abe K, Tanaka T, Saeki Y: Pharmacokinetics of (Me)Arg-Lys-Pro-Trp-tert-Leu-Leu-OEt and (Me)Arg-Lys-Pro-Trp-tert-Leu-Leu administered intravenously to beagle dogs. J Pharm Sci; 1993 Jul;82(7):725-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The pharmacokinetic parameters (mean +/- standard error of mean) after iv administration of NT-1 at 0.1 mg/kg were as follows: the half-life of the distribution phase (t1/2 alpha) was 0.29 +/- 0.11 h, the half-life of the terminal phase (t1/2 beta) was 1.99 +/- 0.41 h, total plasma clearance (CL) was 33.2 +/- 6.3 mL/h/kg, steady-state volume of distribution (Vdss) was 57.1 +/- 2.8 mL/kg, and mean residence time (MRT) was 2.20 +/- 0.55 h.
  • The t1/2 alpha, t1/2 beta, CL, Vdss, and MRT values after iv administration of NT-2 at 0.25 mg/kg were 0.11 +/- 0.02 h, 0.58 +/- 0.04 h, 257.3 +/- 17.2 mL/h/kg, 180.3 +/- 4.6 mL/kg, and 0.71 +/- 0.04 h, respectively.
  • [MeSH-minor] Amino Acid Sequence. Animals. Blood Proteins / metabolism. Chemistry, Physical. Dogs. Half-Life. Injections, Intravenous. Male. Molecular Sequence Data. Physicochemical Phenomena. Protein Binding

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  • (PMID = 8360847.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Blood Proteins; 0 / Oligopeptides; 0 / Peptide Fragments; 0 / methyl(arginyl)-lysyl-prolyl-tryptophyl-tert-leucyl-leucine; 125600-60-4 / methylarginyl-lysyl-prolyl-tryptophyl-tert-leucyl-leucyl-ethyl ester; 39379-15-2 / Neurotensin
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96. Dergunov AD, Vorotnikova YY, De Pauw M, Rosseneu M: Apolipoprotein E self-association in solution studied by non-radiative energy transfer. J Biochem Biophys Methods; 1994 Dec;29(3-4):259-67
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  • ApoE was separately labeled with a fluorescent donor group i.e. dansyl chloride (apoE/D) and with an acceptor i.e. fluorescein isothiocyanate (apoE/F).
  • [MeSH-major] Apolipoproteins E / chemistry. Energy Transfer
  • [MeSH-minor] Chemistry, Physical. Dansyl Compounds. Fluorescein-5-isothiocyanate. Humans. Kinetics. Physicochemical Phenomena. Solutions / chemistry. Spectrometry, Fluorescence

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  • (PMID = 7699203.001).
  • [ISSN] 0165-022X
  • [Journal-full-title] Journal of biochemical and biophysical methods
  • [ISO-abbreviation] J. Biochem. Biophys. Methods
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Apolipoproteins E; 0 / Dansyl Compounds; 0 / Solutions; I223NX31W9 / Fluorescein-5-isothiocyanate; QMU9166TJ4 / dansyl chloride
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97. Dahlbäck B, Hermansson M, Kjelleberg S, Norkrans B: The hydrophobicity of bacteria - an important factor in their initial adhesion at the air-water interface. Arch Microbiol; 1981 Jan;128(3):267-70
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  • [3H]-L-leucine metabolically labeled isolates were run on a column packed with Octyl-Sepharose CL-4B gel.
  • [MeSH-major] Bacterial Physiological Phenomena. Water Microbiology
  • [MeSH-minor] Chemistry, Physical. Physicochemical Phenomena. Solubility. Surface Properties

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  • (PMID = 7212931.001).
  • [ISSN] 0302-8933
  • [Journal-full-title] Archives of microbiology
  • [ISO-abbreviation] Arch. Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] GERMANY, WEST
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98. Sakaguchi M, Webb MW, Agrawal KC: Potential radiosensitizing agents. 4. 2-Nitroimidazole nucleosides. J Med Chem; 1982 Nov;25(11):1339-42
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl and glucothiopyranosyl analogues of 2-nitroimidazole were synthesized by condensation in the presence of stannic chloride and mercuric cyanide.
  • [MeSH-minor] Animals. Cell Survival / drug effects. Cells, Cultured. Chemistry, Physical. Cricetinae. Cricetulus. Gamma Rays. Physicochemical Phenomena

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  • (PMID = 6890579.001).
  • [ISSN] 0022-2623
  • [Journal-full-title] Journal of medicinal chemistry
  • [ISO-abbreviation] J. Med. Chem.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-21050
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Nitroimidazoles; 0 / Radiation-Sensitizing Agents
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99. Vedani A, Meyer EF Jr: Structure-activity relationships of sulfonamide drugs and human carbonic anhydrase C: modeling of inhibitor molecules into the receptor site of the enzyme with an interactive computer graphics display. J Pharm Sci; 1984 Mar;73(3):352-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We also discuss the possibility that the relative inactivity of thiazide diuretics is due to the steric interaction of the ortho chlorine atom with the enzyme receptor cavity.
  • [MeSH-minor] Binding Sites. Chemistry, Physical. Computers. Models, Molecular. Physicochemical Phenomena. Structure-Activity Relationship

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  • (PMID = 6716242.001).
  • [ISSN] 0022-3549
  • [Journal-full-title] Journal of pharmaceutical sciences
  • [ISO-abbreviation] J Pharm Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Carbonic Anhydrase Inhibitors; 0 / Sulfonamides
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100. Garey JR, Riggs AF: Structure and function of hemoglobin from Urechis caupo. Arch Biochem Biophys; 1984 Jan;228(1):320-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Fractions F-I (the major fraction) and F-II are each composed of at least five electrophoretic components.
  • Minor fractions F-III has an amino acid composition which is very different from those of fractions F-I and F-II.
  • Amino acid analysis and peptide mapping suggests that fractions F-I and F-II are very similar, and may differ only in a few post-translational modifications.
  • Oxygen binding is noncooperative, with a pressure of half-saturation (p50) of 12 mm Hg at 20 degrees C and pH 7.5 in Tris buffers.
  • The oxygen equilibrium is not significantly affected by ATP, Cl-, Ca2+, Mg2+, or CO2.
  • The pH dependence of oxygen binding is extremely small: delta Log p50/delta pH is only +0.06 between pH 6 and 7.5.
  • Deoxygenation, oxidation, dilution, or pH changes have no significant effect on the state of aggregation.
  • [MeSH-minor] Amino Acid Sequence. Amino Acids / analysis. Animals. Chemistry, Physical. Humans. Hydrogen-Ion Concentration. Macromolecular Substances. Oxygen / metabolism. Physicochemical Phenomena. Thermodynamics

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  • (PMID = 6696435.001).
  • [ISSN] 0003-9861
  • [Journal-full-title] Archives of biochemistry and biophysics
  • [ISO-abbreviation] Arch. Biochem. Biophys.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Amino Acids; 0 / Hemoglobins; 0 / Macromolecular Substances; S88TT14065 / Oxygen
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