McGuinness J et al: How to reduce hospital-acquired pressure ulcers on a neuroscience unit with a skin and wound assessment
Garau J et al: Current management of patients hospitalized with complicated skin and soft tissue infections across Europe (2010-2011): assessment
of clinical practice patterns and real-life effectiveness of antibiotics from the REACH study. ... Penson DF: Re: comparative effectiveness of skin antiseptic agents in reducing surgical site infections: a report from the washington state surgical care and outcomes assessment
MacKay C et al: From pathways to people: applying the adverse outcome pathway (AOP) for skin sensitization to risk assessment
. ... Chen WY et al: Risk assessment of excess drug and sunscreen absorption via skin
with ablative fractional laser resurfacing : optimization of the applied dose for postoperative care. ... Mackay C et al: From pathways to people: applying the adverse outcome pathway (AOP) for skin sensitization to risk assessment
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin
sensitisation. ... Characterisation of skin sensitisation potential is a key endpoint for the safety assessment
of cosmetic ingredients especially when significant dermal exposure to an ingredient is expected.8.
A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: skin
irritation. ... Evaluation of the skin irritancy and corrosivity potential of an ingredient is a necessity in the safety assessment
of cosmetic ingredients.
The TEA is reported to function as a surfactant or pH adjuster; the related TEA-containing ingredients included in this safety assessment are reported to function as surfactants and hair- or skin
Combined with the data demonstrating little acute toxicity, no skin or ocular irritation, and no reproductive or developmental toxicity, these data form an adequate basis for reaching a conclusion that Dibutyl Adipate is safe as a cosmetic ingredient in the practices of use and concentrations as reflected in this safety assessment
The data needed in order to complete the safety assessment of Cetethyl Morpholinium Ethosulfate include: methods of manufacture and impurities, especially nitrosamines; current concentration of use; skin penetration; if there is significant skin penetration, then both a 28-day dermal toxicity study to assess general skin
and systemic toxicity and a reproductive and developmental toxicity study are needed; two genotoxicity studies, at least one in a mammalian system, if positive, then a 2-year dermal carcinogenisis study using National Toxicology Program (NTP) methods may be needed; ultraviolet (UV) absorption data, if significantly absorbed, then photosensitization data are needed; dermal irritation and sensitization; and ocular toxicity, if available.12.
Pig/minipig is considered a good model for the safety assessment of DNA vaccines due to the similarity to human skin
A skin sensitization safety assessment
of a new bleach activator technology in detergent applications.
Silver-loaded seaweed-based cellulosic fiber improves epidermal skin physiology in atopic dermatitis: safety assessment
, mode of action and controlled, randomized single-blinded exploratory in vivo study.